Results 111 to 120 of about 790,002 (307)

A new twist to coiled coil

FEBS Letters, 2012
Spectrin repeats have been largely considered as passive linkers or spacers with little functional role other than to convey flexibility to a protein. Whilst this is undoubtedly part of their function, it is by no means all. Whilst the overt structure of all spectrin repeats is a simple triple‐helical coiled coil, the linkages between repeats and the ...
Le Rumeur, Elisabeth, Hubert, Jean-François, Winder, Steve   +2 more
openaire   +2 more sources

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Heat exchanger tubes supported in high vibration environment [PDF]

, 1966
Cantilevered structure supports heat exchanger coils against vibration loading while allowing freedom for differential thermal growth. The support channels will accept a variety of coil angles with the same coil pitch, thus reducing the number of parts ...
Urquidi, R.
core   +1 more source

Computational modeling of superparamagnetic nanoparticle-based (affinity) diagnostics

Frontiers in Bioengineering and Biotechnology
IntroductionMagnetic nanoparticles (MNPs), particularly iron oxide nanoparticles (IONPs), are renowned for their superparamagnetic behavior, allowing precise control under external magnetic fields.
Loïc Van Dieren, Loïc Van Dieren, Loïc Van Dieren, Loïc Van Dieren, Loïc Van Dieren, Antoine A. Ruzette, Vlad Tereshenko, Haïzam Oubari, Haïzam Oubari, Haïzam Oubari, Yanis Berkane, Yanis Berkane, Jonathan Cornacchini, Jonathan Cornacchini, Filip Thiessen EF, Filip Thiessen EF, Filip Thiessen EF, Filip Thiessen EF, Curtis L. Cetrulo, Curtis L. Cetrulo, Curtis L. Cetrulo, Curtis L. Cetrulo, Korkut Uygun, Korkut Uygun, Alexandre G. Lellouch, Alexandre G. Lellouch, Alexandre G. Lellouch, Alexandre G. Lellouch, Alexandre G. Lellouch, Alexandre G. Lellouch   +29 more
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Experimental Characterization of Hydronic Air Coil Performance with Aluminum Oxide Nanofluids of Three Concentrations

Applied Nano
This paper presents the continuation of experimental investigations conducted by the present authors to measure and compare the thermal and fluid dynamic performance of a residential hydronic air coil using nanofluids.
Roy Strandberg, Dustin Ray, Debendra K. Das   +2 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

What thermodynamic features characterize good and bad folders? Results from a simplified off-lattice protein model

, 2005
The thermodynamics of the small SH3 protein domain is studied by means of a simplified model where each bead-like amino acid interacts with the others through a contact potential controlled by a 20x20 random matrix.
A. Amatori, A. Fersht, A. Y. Grosberg, C. Micheletti, G. Tiana, J. C. Martinez, J. Ferkinghoff-Borg, P. Flory, R. A. Broglia, R. L. Baldwin   +9 more
core   +1 more source

Endoscopic ultrasound guided emergency coil and glue for actively bleeding duodenal varix after failed endoscopy

Journal of Digestive Endoscopy, 2015
Management of ectopic variceal bleed may be difficult at times due to anatomical location or presence of collaterals. We present a case of an elderly cirrhotic male with acute upper gastrointestinal bleed due to a large duodenal varix successfully ...
Narendra S. Choudhary, Rahul Rai, Puri Rajesh, Sud Randhir   +3 more
doaj   +1 more source

Chirality of Coiled Coils: Elasticity Matters

Physical Review Letters, 2008
Coiled coils are important protein-protein interaction motifs with high specificity that are used to assemble macromolecular complexes. Their simple geometric organization, consisting of alpha helices wrapped around each other, confers remarkable mechanical properties.
Neukirch, S, Goriely, A, Hausrath, A
openaire   +3 more sources