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Molecular basis of coiled-coil formation [PDF]
Coiled coils have attracted considerable interest as design templates in a wide range of applications. Successful coiled-coil design strategies therefore require a detailed understanding of coiled-coil folding. One common feature shared by coiled coils is the presence of a short autonomous helical folding unit, termed “trigger sequence,” that is ...
Steinmetz, Michel O. +8 more
openaire +3 more sources
Introduction: In patients with anterior circulation aneurysmal Subarachnoid Haemorrhage (aSAH), endovascular coiling is currently practiced more frequently than neurosurgical clipping.
Alexander Hamming +4 more
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
A thin stream or rope of viscous fluid falling from a sufficient height onto a surface forms a steadily rotating helical coil. Tabletop laboratory experiments in combination with a numerical model for slender liquid ropes reveal that finite-amplitude ...
Habibi, M. +8 more
core +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Double Negativity in 3D Space Coiling Metamaterials
Metamaterials displaying negative refractive index has remarkable potential to facilitate the manipulation of incident waves for wide variety of applications such as cloaking, superlensing and the like.
SHUKLA, S +3 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A new model is proposed to explain coiling of myelins composed of fluid bilayers. This model allows the constituent bilayer cylinders of a myelin to be non-coaxial and the bilayer lateral tension to vary from bilayer to bilayer.
J. -R. Huang
core +1 more source
Stability of Liquid Rope Coiling
International audienceA thin ‘rope' of viscous fluid falling from a sufficient height coils as it approaches a rigid surface. Here we perform a linear stability analysis of steady coiling, with particular attention to the ‘inertiogravitational' regime in
Habibi, M. +8 more
core +3 more sources
Different antiplatelet regimens for stenting versus coiling for acutely-ruptured cerebral aneurysms
To investigate the safety, efficacy and risk factors for complications of stenting with optional coiling versus coiling alone for acutely ruptured cerebral aneurysms (ARCAs) using different antiplatelet schemes, 2021 patients were prospectively enrolled ...
Li Li +8 more
doaj +1 more source

