Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Coiling Instability of Multilamellar Membrane Tubes with Anchored Polymers
We study experimentally a coiling instability of cylindrical multilamellar stacks of phospholipid membranes, induced by polymers with hydrophobic anchors grafted along their hydrophilic backbone.
A. Goriely +27 more
core +1 more source
Growth and instability of a laminar plume in a strongly stratified environment [PDF]
Experimental studies of laminar plumes descending under gravity into stably stratified environments have shown the existence of a critical injection velocity beyond which the plume exhibits a bifurcation to a coiling instability in three dimensions or a ...
Caulfield, Colm-Cille P. +4 more
core +5 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Stent-assisted reconstructive endovascular repair of intracranial aneurysms: long-term clinical and angiographic follow-up [PDF]
Background and Purpose: The development of self-expanding stents dedicated to intracranial use has significantly widened the applicability of endovascular therapy to many intracranial aneurysms.
VANNUCCI, STEFANO
core
A numerical investigation of the fluid mechanical sewing machine
A thin thread of viscous fluid falling onto a moving belt generates a surprising variety of patterns depending on the belt speed, fall height, flow rate, and fluid properties.
Audoly, Basile +2 more
core +3 more sources
Bio-adhesives from soy protein concentrate and montmorillonite: Rheological and thermal behaviour [PDF]
The incorporation of different amounts of montmorillonite (MMT) to soy protein concentrate (SPC) was used to improve the performance of the bio-nano-adhesive obtained.
Bacigalupe, Alejandro +5 more
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Modulation of water surface waves with a coiling-up-space metasurface
We have designed a gradient-index (GRIN) metasurface to modulate water surface waves (WSWs). The metasurface is composed of an array of coiling-up-space units with a deep sub-wavelength scale, and can focus/scatter WSWs when the units are arranged ...
H. T. Sun +4 more
doaj +1 more source

