Results 51 to 60 of about 4,960 (228)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Impact of aneurysm sac size on the effectiveness of endovascular coiling in patient-specific middle cerebral artery aneurysms: a computational study

open access: yesScientific Reports
This study investigates the hemodynamic efficiency of endovascular coiling in the treatment of patient-specific middle cerebral artery (MCA) aneurysms using computational models of both original and scaled-down geometries.
Zhichao Yao, Hao Wen
doaj   +1 more source

Abstract 11: Impact of Umbilical Coiling Index on Perinatal Outcomes

open access: yesPreventive Medicine: Research & Reviews
Background: The umbilical coiling index (UCI), defined as the ratio of vascular coils to cord length, has been proposed as an indicator of fetal well-being.
Alwi Zaman   +3 more
doaj   +1 more source

Influence of parent vessel feature on the risk of internal carotid artery aneurysm rupture via computational method

open access: yesScientific Reports, 2023
In this study, the role of sac section area and parent vessel diameter on the hemodynamic feature of the blood flow in selected internal carotid artery (ICA) aneurysms is comprehensively investigated.
Mehdi Fattahi   +4 more
doaj   +1 more source

Point--TAR: A Useful Index to Follow-Up Coiled Intracranial Aneurysms? [PDF]

open access: yesAmerican Journal of Neuroradiology, 2014
The Matrix and Platinum Science (MAPS) trial results were recently published showing that Matrix2 coils were not inferior (and not superior) to bare metal coils (BMC) in the treatment of ruptured and unruptured intracranial aneurysms.[1][1] In the trial, 626 patients were enrolled in ...
L, Pierot, J, Fiehler, P, White
openaire   +2 more sources

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Antenatal Umbilical Cord Coiling Index and Adverse Perinatal Outcome: A Prospective Observational Study at A Tertiary Care Hospital in Multan

open access: yesLife and Science
Objective: The study aims to determine the association between antenatal umbilical cord coiling index (aUCI) measured by Color Doppler ultrasonography in the late second trimester and adverse perinatal outcomes.
Atif Latif   +5 more
doaj   +1 more source

MRI Vessel Wall Imaging and Treatment of an Aneurysm at the Atlanto-Axial Segment of an Aberrant Vertebral Artery [PDF]

open access: yesNeurointervention, 2018
We report a case of unique location of an aneurysm at the atlanto-axial extradural segment of a unilateral aberrant vertebral artery. The MRI vessel wall imaging findings and possible mechanism of aneurysm formation were discussed.
Tsang Chun On Anderson   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

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