Results 31 to 40 of about 33,542 (293)
A generalized coincidence point index
Applied General Topology, 2005 The paper is devoted to build for some pairs of continuous single-valued maps a coincidence point index. The class of pairs (f, g) satisfies the condition that f induces an epimorphism of the Cech homology groups with compact supports and coefficients in
N.M. Benkafadar, M.C. Benkara-Mostefa
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FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
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Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
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Open Mathematics, 2019 Overf the last few years, by utilizing Mawhin’s continuation theorem of coincidence degree theory and Lyapunov functional, many scholars have been concerned with the global asymptotical stability of positive periodic solutions for the non-linear ...
Han Sufang +4 more
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The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
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Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
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Mathematical Modelling and Analysis, 2010 By using the Mawhin continuation theorem of coincidence degree theory and some results on inequalities, we establish the existence of 2 n positive periodic solutions for n species non‐autonomous Lotka‐Volterra unidirectional food chains with harvesting ...
Yongkun Li, Kaihong Zhao
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Existence of solutions for a higher order Riemann–Liouville fractional differential equation by Mawhin's coincidence degree theory [PDF]
, 2023 Alexander Domoshnitsky +2 more
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