Results 31 to 40 of about 36,323 (288)

Tracking Health Related Quality of Life From Diagnosis to Follow‐Up Among Australian Children With Acute Lymphoblastic Leukaemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukaemia (ALL) is one of the most treatable forms of paediatric cancer; however, there is a substantial burden of treatment‐related toxicities (TRTs). In addition, the long‐term changes in children's health‐related quality of life (HRQoL) due to toxic treatments are not well understood.
Clare Ghows   +19 more
wiley   +1 more source

Random coincidence degree theory with applications to random differential inclusions [PDF]

open access: yes, 1996
summary:The aim of this paper is to establish a random coincidence degree theory. This degree theory possesses all the usual properties of the deterministic degree theory such as existence of solutions, excision and Borsuk's odd mapping theorem.
Tarafdar, E., Yuan, Xian-Zhi, Watson, P.
core  

Coincidence Theory of a Nonlinear Periodic Sturm–Liouville System and Its Applications [PDF]

open access: yes, 2022
Based on the second derivative, this paper directly establishes the coincidence degree theory of a nonlinear periodic Sturm–Liouville (SL) system. As applications, we study the existence of periodic solutions to the S–L system with some special nonlinear
Kaihong Zhao
core   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Maps between surfaces and minimal coincidence sets for homotopies [PDF]

open access: yes, 2001
In this paper we consider the 1-parameter coincidence problem of finding homotopies of pairs of maps (ft,gt) such that the number of coincidence points is independent of t.
Kelly, M.R., Gonçalves, D.L.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Multiplicity of positive periodic solutions in the superlinear indefinite case via coincidence degree [PDF]

open access: yes, 2017
We study the periodic boundary value problem associated with the second order nonlinear differential equation u'' + c u' + (a^+(t) - μ a^-(t)) g(u) = 0, where g(u) has superlinear growth at zero and at infinity, a(t) is a periodic sign-changing weight, c∈
Zanolin, Fabio, Feltrin, Guglielmo
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Holographic dark energy and cosmic coincidence [PDF]

open access: yes, 2005
In this Letter we demonstrate that any interaction of pressureless dark matter with holographic dark energy, whose infrared cutoff is set by the Hubble scale, implies a constant ratio of the energy densities of both components thus solving the ...
Zimdahl, Winfried, Pavón, Diego
core   +1 more source

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