Results 51 to 60 of about 35,903 (255)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
On the structure of the set of coincidence points
Sbornik: Mathematics, 2015 We consider the set of coincidence points for two maps between metric spaces. Cardinality, metric and topological properties of the coincidence set are studied. We obtain conditions which guarantee that this set (a) consists of at least two points; (b) consists of at least n points; (c) contains a countable subset; (d) is uncountable.
Arutyunov A.V., Gel'man B.D.
openaire +3 more sources
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
New Nonlinear Conditions and Inequalities for the Existence of Coincidence Points and Fixed Points
Journal of Applied Mathematics, 2012 Some new fixed point theorems for nonlinear maps are established. By using these results, we can obtain some new coincidence point theorems. Our results are quite different in the literature and references therein.
Wei-Shih Du, Shao-Xuan Zheng
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Coincidence and fixed points for compatible and relatively nonexpansive maps
International Journal of Mathematics and Mathematical Sciences, 1993 The concept of relatively nonexpansive maps is introduced. Fixed point and coincidence results for families of four self maps of metric spaces are obtained.
Gerald Jungck
doaj +1 more source
A New Technique to Compute Coupled Coincidence Points [PDF]
Chinese Journal of Mathematics, 2014 We compute coupled coincidence points without assuming the condition of compatibility of the pair of maps and relaxing the continuity condition of both the maps. In fact, our technique improves the technique introduced by Sintunavarat et al. (2011) which was then used by Hussain et al. (2012) to obtain coupled coincidence points.
Jain, Manish +2 more
openaire +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
On Coincidence and Fixed-Point Theorems in Symmetric Spaces [PDF]
Fixed Point Theory and Applications, 2008 AbstractWe give an axiom (C.C) in symmetric spaces and investigate the relationships between (C.C) and axioms (W3), (W4), and (H.E). We give some results on coinsidence and fixed-point theorems in symmetric spaces, and also, we give some examples for the results of Imdad et al. (2006).
Jong-Sook Bae +2 more
openaire +4 more sources