Results 61 to 70 of about 35,903 (255)
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Coincidence Points and Common Fixed Points of Cyclic Maps by Implicit Contractive Conditions
The study of common fixed points and coincidence points has occupied a large part of the priorities of researchers, especially in the metric space and its generalizations.
Abbas Karim Nahi, Salwa Salman Abed
doaj +1 more source
Abstract Leray–Schauder Type Alternatives and Extensions
We present a Leray–Schauder type alternative for a general class of maps. This enables us to obtain some Birkhoff–Kellogg type results and a Furi–Pera result.
O’Regan Donal
doaj +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Leray–Schauder Alternatives for Maps Satisfying Countable Compactness Conditions
In this paper we present Leray–Schauder alternatives for a general class of Mönch type maps.
O’Regan Donal
doaj +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Remarks on recent fixed point theorems for compatible maps
Following Gerald Jungck's formulation of compatibility of maps, several interesting fixed point theorems for such maps have been obtained, wherein at least one of the maps is continuous.
S. L. Singh, V. Chadha, S. N. Mishra
doaj +1 more source
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley +1 more source
Coincidence Best Proximity Points of Proximal Berinde G-Contractions
Recently, a concept of proximal Berinde contractions was introduced and applied to prove the existence of coincidence best proximity points in metric spaces. In this article, we established a new approach to show that these results can be obtained from a
Moosa Gabeleh, Jack Markin
doaj +1 more source

