Results 61 to 70 of about 2,325,941 (278)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Coincidence points principle for set-valued mappings in partially ordered spaces

, 2020
In the paper the concept of covering (regularity) for set-valued mappings in partially ordered spaces is introduced. The coincidence points problem for set-valued mappings in partially ordered spaces is considered. Sufficient conditions for the existence
Zhukovskiy S.E., Arutyunov A.V., Zhukovskiy E.S.   +2 more
core   +2 more sources

Topological Transversality Coincidence Theory for Multivalued Maps with Selections in a Given Class

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2021
This paper presents the topological transversality coincidence theorem for general multivalued maps who have selections in a given class of maps.
O’Regan Donal
doaj   +1 more source

EXISTENCE AND STABILITY RESULTS FOR COINCIDENCE POINTS OF NONLINEAR CONTRACTIONS [PDF]

, 2017
In this paper we define $\alpha$ - admissibility of multi-valued mapping with respect to a single-valued mapping and use this concept to establish a coincidence point theorem for pairs of nonlinear multi-valued and single-valued mappings under the ...
Metiya, Nikhilesh, Choudhury, Binayak S., Kundu, Sunirmal   +2 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A generalized coincidence point index

Applied General Topology, 2005
The authors acknowledge the support of A.N.D.R.U., (Contract No 03/06 Code CU 19905) and M.E.R.S., (Project No B*2501/04/04), Laboratory M.M.E.R.E.
Benkafadar, N.M., Benkara-Mostefa, M.C.
openaire   +4 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Coincidences and colorings of lattices and Z-modules [PDF]

, 2010
Loquias M. Coincidences and colorings of lattices and Z-modules. Bielefeld (Germany): Bielefeld University; 2010.This thesis delves into the coincidence problem for sublattices and submodules, colorings of lattices and Z-modules, shifted lattices and ...
Loquias, Manuel
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Some results on fixed and coincidence points for pairs of maps in metric spaces [PDF]

, 1993
Following ideas of Dugundji and Granas, some general results are established on the existence of fixed and coincidence points for a pair of maps on metric spaces.
Rodríguez Montes, Jaime
core