Results 71 to 80 of about 357,854 (283)

Some remarks on the attractor behaviour in ELKO cosmology

open access: yes, 2014
Recent results on the dynamical stability of a system involving the interaction of the ELKO spinor field with standard matter in the universe have been reanalysed, and the conclusion is that such system does not exhibit isolated stable points that could ...
da Silva, J. M. Hoff   +2 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Abstract Leray–Schauder Type Alternatives and Extensions

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2019
We present a Leray–Schauder type alternative for a general class of maps. This enables us to obtain some Birkhoff–Kellogg type results and a Furi–Pera result.
O’Regan Donal
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Leray–Schauder Alternatives for Maps Satisfying Countable Compactness Conditions

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2019
In this paper we present Leray–Schauder alternatives for a general class of Mönch type maps.
O’Regan Donal
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Coincidence Analysis Of Point Processes

open access: yes, 2004
Publication in the conference proceedings of EUSIPCO, Viena, Austria ...
Picinbono, Bernard, Bendjaballah, Cherif
openaire   +1 more source

Remarks on recent fixed point theorems for compatible maps

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1996
Following Gerald Jungck's formulation of compatibility of maps, several interesting fixed point theorems for such maps have been obtained, wherein at least one of the maps is continuous.
S. L. Singh, V. Chadha, S. N. Mishra
doaj   +1 more source

Positive coincidence points for a class of nonlinear operators and their applications to matrix equations

open access: yesOpen Mathematics, 2020
Consider an ordered Banach space and f,gf,g two self-operators defined on the interior of its positive cone. In this article, we prove that the equation f(X)=g(X)f(X)=g(X) has a positive solution, whenever f is strictly α\alpha -concave g-monotone or ...
Kedim Imed   +2 more
doaj   +1 more source

Some fixed point results of generalized $$(\phi , \psi )$$ ( ϕ , ψ ) -contractive mappings in ordered b-metric spaces

open access: yesBMC Research Notes, 2020
Objectives The aim of this paper is to establish some fixed point, coincidence point and, coupled coincidence and coupled common fixed point results for generalized $$(\phi , \psi )$$ ( ϕ , ψ ) -contractive mappings in partially ordered b-metric spaces ...
Belay Mitiku   +2 more
doaj   +1 more source

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