Results 81 to 90 of about 2,325,941 (278)

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Coincidence Points and Common Fixed Points of Cyclic Maps by Implicit Contractive Conditions

open access: yesمجلة بغداد للعلوم
The study of common fixed points and coincidence points has occupied a large part of the priorities of researchers, especially in the metric space and its generalizations.
Abbas Karim Nahi, Salwa Salman Abed
doaj   +1 more source

Abstract Leray–Schauder Type Alternatives and Extensions

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2019
We present a Leray–Schauder type alternative for a general class of maps. This enables us to obtain some Birkhoff–Kellogg type results and a Furi–Pera result.
O’Regan Donal
doaj   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle   +4 more
wiley   +1 more source

Leray–Schauder Alternatives for Maps Satisfying Countable Compactness Conditions

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2019
In this paper we present Leray–Schauder alternatives for a general class of Mönch type maps.
O’Regan Donal
doaj   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

Remarks on recent fixed point theorems for compatible maps

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1996
Following Gerald Jungck's formulation of compatibility of maps, several interesting fixed point theorems for such maps have been obtained, wherein at least one of the maps is continuous.
S. L. Singh, V. Chadha, S. N. Mishra
doaj   +1 more source

Some fixed point results of generalized $$(\phi , \psi )$$ ( ϕ , ψ ) -contractive mappings in ordered b-metric spaces

open access: yesBMC Research Notes, 2020
Objectives The aim of this paper is to establish some fixed point, coincidence point and, coupled coincidence and coupled common fixed point results for generalized $$(\phi , \psi )$$ ( ϕ , ψ ) -contractive mappings in partially ordered b-metric spaces ...
Belay Mitiku   +2 more
doaj   +1 more source

Paramagnetic Rim Lesions and Choroid Plexus Volume at Diagnosis Are Associated With Cognitive Progression Independent of Relapse and MRI Activity in Early Relapsing–Remitting Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) and choroid plexus (CP) enlargement reflect smoldering inflammation in multiple sclerosis. Their role in cognitive progression remains unexplored. Eighty‐seven early relapsing–remitting MS patients were enrolled at diagnosis and followed longitudinally.
Stefano Ziccardi   +15 more
wiley   +1 more source

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