Results 181 to 190 of about 45,519 (269)

Chronic Recurrent Idiopathic Pericardial Effusion in a 53‐Year‐Old With Down Syndrome: A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Pericardial effusion can result from multiple causes, and patients with Down syndrome are at increased risk. We report a case of idiopathic pericardial effusion in a Down syndrome patient, highlighting ECG as an important diagnostic feature for timely and effective management of this condition.
Rossana Izzo   +8 more
wiley   +1 more source

Common Femoral Vein Wall Thickness as a Diagnostic Marker for Behçet's Disease: A Case‐Control Study

open access: yesHealth Science Reports, Volume 8, Issue 10, October 2025.
ABSTRACT Background and Aims Recent publications have highlighted the potential diagnostic value of measuring common femoral vein (CFV) wall thickness in Behçet's Disease (BD). The diagnosis of BD remains a clinical challenge. The objective of this study is to evaluate the utility of venous Doppler ultrasound measurement of CFV wall thickness as a ...
Raghad Tarcha   +3 more
wiley   +1 more source

Hypertrophic Scarring and Keloids: Epidemiology, Molecular Pathogenesis, and Therapeutic Interventions

open access: yesMedComm, Volume 6, Issue 10, October 2025.
Hypertrophic scars and keloids highlight distinct epidemiology, multifactorial triggers (genetic, mechanical, medical), and dysregulated signaling hubs (TGF‐β, Integrin‐FAK, Wnt/β‐catenin). Emerging interventions targeting fibroblast plasticity, inflammation, and biomechanics via gene editing, immune modulation, and biomaterials are increasingly ...
Xiaowan Fang   +7 more
wiley   +1 more source

Acute Myocardial Infarction: Molecular Pathogenesis, Diagnosis, and Clinical Management

open access: yesMedComm, Volume 6, Issue 10, October 2025.
Key pathogenic mechanisms in AMI. Oxidative stress and mitochondrial dysfunction induce ROS accumulation, while DAMPs‐PRRs interaction triggers inflammatory cascades. Programmed cell death pathways and epigenetic regulation collectively constitute the core components of AMI pathogenesis.
Mengmeng Zhu   +5 more
wiley   +1 more source

FÉCONDATION in vitro EN PRÉSENCE DE COLCHICINE ET POLYPLOIDIE EXPÉRIMENTALE CHEZ LE LAPIN [PDF]

open access: bronze, 1962
Ondine BOMSFL-HELMREICH   +2 more
openalex   +1 more source

Discovery of natural product derivative triptolidiol as a direct NLRP3 inhibitor by reducing K63‐specific ubiquitination

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 20, Page 4876-4893, October 2025.
▪ Background and Purpose NLRP3 is up‐regulated in inflammatory and autoimmune diseases. The development of NLRP3 inhibitors is challenged by the identification of compounds with distinct mechanisms of action avoiding side effects and toxicity. Triptolide is a natural product with multiple anti‐inflammatory activities, but a narrow therapeutic window ...
Mo‐Yu Ding   +5 more
wiley   +1 more source

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