Results 161 to 170 of about 16,654 (233)
Konda, Chandana, Rao, Angoori Gnaneshwar
openaire +2 more sources
Management of Acute Colchicine Poisoning With Multiple Organ Dysfunction Syndrome: A Case Report
ABSTRACT Colchicine is a microtubule‐disrupting alkaloid used in the treatment of gout and familial Mediterranean fever. It has a narrow therapeutic window, and overdose is associated with a high risk of fatal toxicity. Colchicine poisoning may initially present with gastrointestinal symptoms resembling acute gastroenteritis, which can make early ...
Jintao Luo +6 more
wiley +1 more source
ABSTRACT Background Reports of immune checkpoint inhibitor (ICI) therapy‐associated immune‐related adverse events (irAEs) exhibit considerable heterogeneity, particularly when comparing data from clinical trials and real‐world observational studies. Methods We conducted a systematic review of real‐world observational studies (case reports and series ...
Shea‐Lee Godin +4 more
wiley +1 more source
Puerarin‐Loaded Macrophage‐Derived Exosomes for Experimental Atherosclerosis
We developed a macrophage‐derived exosome‐based delivery system to enhance the therapeutic efficacy of puerarin (Pue) against atherosclerosis (AS). Exosomes were isolated from RAW264.7 cells, co‐cultured with Pue, and comprehensively characterized for morphology, stability, and drug loading.
Zijian Zou +6 more
wiley +1 more source
Natural Product‐Derived Vesicles in Nanotherapeutics
Natural product‐derived vesicles (NPVs) are an emerging nature‐based nanotherapeutic that can deliver bioactive metabolites into the target site and induce beneficial mechanisms. A practical, chronological bench‐to‐bedside approach throughout the entire NPV development process is expected to resolve challenges encountered in NPV studies.
Kartiko Arif Purnomo, Tsong‐Long Hwang
wiley +1 more source
THE ANTIBACTERIAL ACTION OF COLCHICINE AND COLCHICEINE
M A, GOHAR, M, MAKKAWI
openaire +2 more sources
ABSTRACT Background A 34‐year‐old man presented to our primary care clinic with persistent pain and swelling of the right first metatarsophalangeal joint lasting 3 months. A previous clinic had suspected gout based on hyperuricemia, but urate‐lowering therapy was repeatedly withheld because of ongoing inflammation, resulting in prolonged symptoms ...
Takayuki Yamada
wiley +1 more source
Longitudinal 1H and 129Xe Lung MRI in Patients With Post‐COVID Residual Lung Abnormalities
ABSTRACT Background It is unclear how lung function may recover in patients with residual lung abnormalities (RLAs) following COVID‐19 pneumonia. Purpose To evaluate lung function trends over time in patients with RLAs following hospitalization due to COVID‐19. Study Type Prospective, multicenter longitudinal cohort study.
Laura C. Saunders +41 more
wiley +1 more source
Obesity and hypertension co‐exist and share molecular mechanisms in terms of dietary therapy, modulated by food bioactive constituents. ABSTRACT Obesity and hypertension are among the most pressing global public health challenges. They frequently co‐exist, with obesity‐related hypertension accounting for an estimated 75% of the hypertension burden ...
Samuel Oluwasegun Maccarthy +3 more
wiley +1 more source
Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen +7 more
wiley +1 more source

