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Trends in Cardiovascular Medicine, 2015
Colchicine is one of the oldest available drugs. It has been used for centuries to treat and prevent gouty attacks and more recently to prevent attacks of autoinflammatory diseases such as Familial Mediterranean Fever. Its main mechanism of action is the capability to block the polymerization of tubulin, thus affecting the function of microtubules. The
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Colchicine is one of the oldest available drugs. It has been used for centuries to treat and prevent gouty attacks and more recently to prevent attacks of autoinflammatory diseases such as Familial Mediterranean Fever. Its main mechanism of action is the capability to block the polymerization of tubulin, thus affecting the function of microtubules. The
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Experientia, 1953
Expose d'une nouvelle hypothese sur l'origine biochimique de la colchicine dans la plante. Il est suppose que l'acide trihydroxyphenylpyruvique agit commeprecurseur de cet alcaloide en subissant les transformations decrites par les formules (I) a (VI).
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Expose d'une nouvelle hypothese sur l'origine biochimique de la colchicine dans la plante. Il est suppose que l'acide trihydroxyphenylpyruvique agit commeprecurseur de cet alcaloide en subissant les transformations decrites par les formules (I) a (VI).
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Australasian Annals of Medicine, 1968
SUMMARYA case of self‐administered overdosage of colchicine is described. Despite gastrointestinal, hærnopoietic, neurological, hepatic and renal damage, together with alopecia, stomatitis, fever,transient hypertension and arthralgia, the patient survived.This wide range of toxic effects has been recorded in animal experiments, but seldom occurs in ...
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SUMMARYA case of self‐administered overdosage of colchicine is described. Despite gastrointestinal, hærnopoietic, neurological, hepatic and renal damage, together with alopecia, stomatitis, fever,transient hypertension and arthralgia, the patient survived.This wide range of toxic effects has been recorded in animal experiments, but seldom occurs in ...
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Effect of Colchicine on Myocardial Injury in Acute Myocardial Infarction
Circulation, 2021Didier Bresson +2 more
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