Results 181 to 190 of about 50,572 (275)

Acetylation Variability in Elderly Tunisians: Implications for Isoniazid Dose Individualization

The Journal of Clinical Pharmacology, Volume 66, Issue 6, June 2026.
Abstract The relationship between age and isoniazid acetylation phenotype remains insufficiently characterized, particularly in elderly populations, where pharmacokinetic variability and susceptibility to toxicity may be increased. This study aimed to characterize isoniazid acetylation phenotypes in elderly Tunisian patients using a phenotypic index ...
Yasmine Khefacha, Syrine Ben‐Hammamia, Mouna Ben Sassi, Khouloud Ferchichi, Mouna Daldoul, Hanene El Jebari, Mohamed Zouari, Issam Salouage, Rim Charfi, Riadh Daghfous, Emna Gaies, Sameh Trabelsi   +11 more
wiley   +1 more source

Differential effects of semaglutide and colchicine on atrial remodeling in rats with reduced ejection fraction after myocardial infarction. [PDF]

Europace
Levi O, Dalal N, Komissar A, Moldavsky D, Khamaisi S, Elyagon S, Murninkas M, Eliyahu A, Burg S, Attali B, Makarovsky D, Lichtenstein A, Gradwohl G, Tsaban G, Kakzanov Y, Laish-Farkash A, Etzion S, Etzion Y.   +17 more
europepmc   +1 more source

Acute Pericardial Effusion After Vein of Marshall Ethanol Infusion for Persistent Atrial Fibrillation

Journal of Arrhythmia, Volume 42, Issue 3, June 2026.
This study reports a 25.2% incidence of acute pericardial effusion following vein of Marshall ethanol infusion for persistent atrial fibrillation. The extent of the resulting low‐voltage area was identified as an independent predictor of pericardial effusion, reflecting the magnitude of chemical injury.
Hualong Li, Jianlong Yin, Jian Liang, Ning Huang, Teng Li   +4 more
wiley   +1 more source

Surgical Reconstruction in Pyoderma Gangrenosum, a Retrospective Study of Five Patients

JEADV Clinical Practice, Volume 5, Issue 2, Page 632-636, June 2026.
ABSTRACT Pyoderma Gangrenosum (PG) is a neutrophilic dermatosis characterized by chronic painful ulcerations most commonly on the lower extremities. Current treatment options for PG are largely nonsurgical and include the use of systemic and topical immunomodulators and wound care.
Max E. Oscherwitz, Alysia B. Kohrs, Jacob C. Maus, Matthew L. Hrin, Maria C. Mariencheck, Joseph L. Jorizzo, Kyle E. Robinson, Joseph A. Molnar, Lindsay C. Strowd   +8 more
wiley   +1 more source

Colchicine in Cardiovascular Disease: Evidence Structure, Clinical Efficacy, Safety, and Translational Positioning Across Cardiovascular Syndromes. [PDF]

Int J Mol Sci
Omidian H, Cubeddu LG, Gill EJ, Cubeddu LX.   +3 more
europepmc   +1 more source

Clinical Features and Therapeutic Outcomes in Pyoderma Gangrenosum: A Prospective Cohort Study

JEADV Clinical Practice, Volume 5, Issue 2, Page 495-501, June 2026.
ABSTRACT Background Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis highly associated with systemic comorbidities. Accurate diagnosis and treatment remain challenging due to its rarity and clinical mimickers. Objectives To evaluate demographic, clinical features and treatment outcomes in patients referred with suspected PG at a tertiary ...
David Croitoru, Nesrine Brahimi, Haleh Zabihi, Cathryn Sibbald, Kyle Seigel, Delaram Shojaei, Eric McMullen, Afsaneh Alavi, Lily Archaempong, Aaron M. Drucker, Adam Weizman, Kenneth Croitoru, Robert Inman, Vincent Piguet   +13 more
wiley   +1 more source

The therapeutic potential of colchicine in oncology studies: from structural modification and targeted delivery to clinical management. [PDF]

Front Pharmacol
Jin P, Wu S, Yao H, Ni Y, Yuan Z, Che A, Tian L, Li J.   +7 more
europepmc   +1 more source

THE ANTIBACTERIAL ACTION OF COLCHICINE AND COLCHICEINE

Journal of Pharmacy and Pharmacology, 1951
M A, GOHAR, M, MAKKAWI
openaire   +2 more sources

Pharmacological Modulation of Injury-Induced Vascular Remodeling by Colchicine: An Integrated Experimental and Network-Based Analysis. [PDF]

Biomedicines
Onar LC, Guner E, Yumun HNA, Dindar H, Yilmaz I, Yumun G.   +5 more
europepmc   +1 more source

Therapeutic Options for IgA Pemphigus in Patients Refractory to Dapsone

JEADV Clinical Practice, Volume 5, Issue 2, Page 415-424, June 2026.
ABSTRACT IgA pemphigus is a rare autoimmune blistering disorder with limited therapeutic guidance available due to its rarity and complex presentation. This comprehensive analysis evaluates the therapeutic outcomes of 67 published patients, emphasising the significant role of dapsone as the first‐line treatment.
Lorenz Frasheri, Marta Dechant, Tilo Biedermann   +2 more
wiley   +1 more source