Results 31 to 40 of about 338,876 (258)

The molecular basis of the effect of temperature on enzyme activity

, 2010
Experimental data show that the effect of temperature on enzymes cannot be adequately explained in terms of a two-state model based on increases in activity and denaturation.
Oudshoorn, Matthew Leslie, Kelly, S.M., Price, N.C., Weinberg, C.S., Monk, C.R., Oudshoorn, M.L., Monk, Colin R., Danson, Michael J., Price, Nicholas C., Danson, M.J., Lee, Charles Kai-Wu, Peterson, Michelle E., Lee, C.K., Peterson, M.E., Weinberg, Cristina S., Daniel, R.M., Daniel, Roy M., Kelly, Sharon M.   +17 more
core   +1 more source

Immobilization of Cold-Active Cellulase from Antarctic Bacterium and Its Use for Kelp Cellulose Ethanol Fermentation

BioResources, 2015
Immobilization is an effective way to solve the problem associated with the application of cold-active cellulase in industrial processes. In this study, a cold-active cellulase from the Antarctic psychrophilic bacterium Pseudoalteromonas sp.
Yi Bin Wang, Cong Gao, Zhou Zheng, Fang Ming Liu, Jia Ye Zang, Jin Lai Miao   +5 more
doaj   +1 more source

Effects of chronic cold treatment on root elongation and gene expression in "Arabidopsis thaliana" [PDF]

, 2008
Low temperature is a major limitation of plant growth. Cold adaptation is important for the survival and distribution of plant species at high elevations and high latitudes.
Lee, Yang Ping
core   +1 more source

Active droplets through enzyme-free, dynamic phosphorylation

, 2023
Life continuously transduces energy to perform critical functions using energy stored in reactive molecules like ATP or NADH. ATP dynamically phosphorylates active sites on proteins and thereby regulates their function.
Michele, Stasi, Judit, Sastre, Monika , Wenisch, Brigitte , Kriebisch, Simone , Poprawa, Job, Boekhoven   +5 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Evolution of substrate specificity in a recipient's enzyme following horizontal gene transfer [PDF]

, 2013
Despite the prominent role of horizontal gene transfer (HGT) in shaping bacterial metabolism, little is known about the impact of HGT on the evolution of enzyme function.
Noda-Garcia, Lianet, Medina-Ruíz, Sophía, Gaytán, Paul, Carrillo-Tripp, Mauricio, Camacho-Zarco, Aldo R., Fülöp, Vilmos, Barona-Gómez, Francisco   +6 more
core   +1 more source

Structural and functional characterization of cold-active sialidase isolated from Antarctic fungus Penicillium griseofulvum P29

Biochemistry and Biophysics Reports
The fungal strain, Penicillium griseofulvum P29, isolated from a soil sample taken from Terra Nova Bay, Antarctica, was found to be a good producer of sialidase (P29).
Aleksandar Dolashki, Radoslav Abrashev, Dimitar Kaynarov, Ekaterina Krumova, Lyudmila Velkova, Rumyana Eneva, Stefan Engibarov, Yana Gocheva, Jeny Miteva-Staleva, Vladislava Dishliyska, Boryana Spasova, Maria Angelova, Pavlina Dolashka   +12 more
doaj   +1 more source

Optimizing and purifying extracellular cold- active lipase from Talaromyces pinophilus AUMC 308 for potential use in industrial detergents [PDF]

Assiut University Journal of Multidisciplinary Scientific Research
In this study, a strain of Talaromyces pinophilus AUMC 308 was used. The 15th days of fermentation at pH 6.0, 15°C with ammonium chloride as the nitrogen source were shown to be the optimal settings for the synthesis of the enzyme.
Asmaa M.A. Omar, Abdel-Nasser A. Zohri, Ahmed Y. Abdel-Malek, Osama Abdel-Hafeez Mohamed Al-Bedak   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

MACiE: a database of enzyme reaction mechanisms.

, 2005
SUMMARY: MACiE (mechanism, annotation and classification in enzymes) is a publicly available web-based database, held in CMLReact (an XML application), that aims to help our understanding of the evolution of enzyme catalytic mechanisms and also to create
Gemma L. Holliday, Bartlett, G J, Noel M. O'Boyle, Janet M. Thornton, O'Boyle, N M, Peter Murray-Rust, John B. O. Mitchell, Holliday, G L, Almonacid, D E, Murray-Rust, P, Daniel E. Almonacid, Thornton, J M, Mitchell, John Blayney Owen, Gail J. Bartlett   +13 more
core   +1 more source