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Cold-Adapted and Mesophilic Brachyurins
Biological Chemistry, 2002Two different types of brachyurins, termed I and II, have been described in the literature. Within type I there are two subtypes, Ia and Ib. The prototype for the type I brachyurins is Fiddler crab collagenase I. Its cold-adapted analogue from Antarctic krill, termed euphaulysin, shares many of its characteristics.
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2001
In the last few years, increased attention has been focused on enzymes produced by cold-adapted micro-organisms. It has emerged that psychrophilic enzymes represent an extremely powerful tool in both protein folding investigations and for biotechnological purposes. Such enzymes are characterised by an increased thermosensitivity and, most of them, by a
D. Georlette +12 more
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In the last few years, increased attention has been focused on enzymes produced by cold-adapted micro-organisms. It has emerged that psychrophilic enzymes represent an extremely powerful tool in both protein folding investigations and for biotechnological purposes. Such enzymes are characterised by an increased thermosensitivity and, most of them, by a
D. Georlette +12 more
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Cold Adaptation in DEAD-Box Proteins
Biochemistry, 2010Spontaneous rearrangements of RNA structures are usually characterized by large activation energies and thus become very slow at low temperatures, yet RNA structure must remain dynamic even in cold-adapted (psychrophilic) organisms. DEAD-box proteins constitute a ubiquitous family of RNA-dependent ATPases that can often unwind short RNA duplexes in ...
Gwendoline, Cartier +4 more
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Cold Adaptation of Enzyme Reaction Rates
Biochemistry, 2008A major issue for organisms living at extreme temperatures is to preserve both stability and activity of their enzymes. Cold-adapted enzymes generally have a reduced thermal stability, to counteract freezing, and show a lower enthalpy and a more negative entropy of activation compared to mesophilic and thermophilic homologues.
Sinisa, Bjelic +2 more
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Long-term cold adaptation in the rat
Comparative Biochemistry and Physiology Part A: Physiology, 19881. To determine whether long-term cold exposure induces insulative adaptation in the rat, two groups of eight adult animals each were exposed to 4 and 25 degrees C, respectively, for 18 months. 2. At any ambient temperature between -5 and 30 degrees C, the cold adapted animals had a higher rate of oxygen uptake, and higher unfurred skin temperatures ...
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MATERNAL PROCESSES IN THE COLD‐ADAPTATION OF MICE
Biological Reviews, 1973SUMMARY Both laboratory and wild house mice, Mus musculus, given bedding, can breed in captivity in an environment kept at – 3°C. The nest temperature when a young litter is present then fluctuates widely. In a typical laboratory (at 21°C) the temperature of the nest is both higher and more constant. The ovaries of pregnant mice breeding at – 3°C have
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Cold adaptation as a life style strategy
Medical Hypotheses, 2003Humans evolved in Africa, where climate would have required cold adaptation. Modern humans have housing which separates them from the environment. Metabolic disorders are prevalent in populations with excess Western diet and lack of exercise. A thrifty genotype has been proposed as an explanation for susceptibility.
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