Results 61 to 70 of about 1,462,869 (311)
Supporting evidence-based adaptation decision-making in Queensland: a synthesis of climate change adaptation research [PDF]
This research synthesis provides policy-makers and practitioners with an understanding of the building blocks for effective adaptation decision-making, as evidenced through the NCCARF research program.
Jennifer Cane
core
The rumen microbiota plays an important role in animal functional attributes. These microbes are indispensable for the normal physiological development of the rumen, and may also convert the plant polysaccharides from grass into available milk and meat ...
Huan Li +9 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Framing adaptation in the Victorian context: synthesis report [PDF]
This synthesis report provides a summary of the research activity and conveys the key findings arising from the 18 month ‘Framing Adaptation in the Victorian Context’ project undertaken between 2010 and 2012.
Hartmut Funfgeld, Darryn McEvoy
core
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Exercise Does Not Prevent Thermoregulatory Adaptation to Cold Stress During the Winter Season [PDF]
PURPOSE Despite the growing need for recreation and work in cold environments, which often involve high levels of physical activity and significant body heat loss, studies investigating the impact of exercise during repeated cold exposure on cold ...
Dae-Hwan Kim +3 more
doaj +1 more source
Supporting evidence-based adaptation decision-making in the Australian Capital Territory: a synthesis of climate change adaptation research [PDF]
This research synthesis provides policy-makers and practitioners with an understanding of the building blocks for effective adaptation decision-making, as evidenced through the NCCARF research program.
Jennifer Cane
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Arthrobacter are commonly isolated from cold soil environments globally, including those that regularly reach sub-freezing temperatures, suggesting that Arthrobacter have significant potential for growth and activity under temperature and stress extremes.
Claudia Wood +6 more
doaj +1 more source

