Results 61 to 70 of about 1,870,769 (208)
Valuing adaptation under rapid change [PDF]
, 2013 The methods used to plan adaptation to climate change have been heavily influenced by scientific narratives of gradual change and economic narratives of marginal adjustments to that change.
Celeste Young +2 more
core
Ecological IndicatorsIn recent decades, alpine meadows have experienced severe degradation owing to external disturbances. Although soil microorganisms are critical for ecosystem services, little is known about their responses to soil degradation and the potential patterns ...
Yu Sun +9 more
doaj +1 more source
Supporting evidence-based adaptation decision-making in the Australian Capital Territory: a synthesis of climate change adaptation research [PDF]
, 2013 This research synthesis provides policy-makers and practitioners with an understanding of the building blocks for effective adaptation decision-making, as evidenced through the NCCARF research program.
Jennifer Cane
core
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Structure and function of hemoproteins from cold-adapted organism [PDF]
, 2011 Environmental oxygen availability certainly plays a key role in the evolution of polar marine life, as suggested by the physiological and biochemical strategies that the organisms have adopted to acquire, deliver and scavenge oxygen.
Russo, Roberta
core +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Exercise Does Not Prevent Thermoregulatory Adaptation to Cold Stress During the Winter Season [PDF]
운동과학PURPOSE Despite the growing need for recreation and work in cold environments, which often involve high levels of physical activity and significant body heat loss, studies investigating the impact of exercise during repeated cold exposure on cold ...
Dae-Hwan Kim +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Frontiers in MicrobiologyArthrobacter are commonly isolated from cold soil environments globally, including those that regularly reach sub-freezing temperatures, suggesting that Arthrobacter have significant potential for growth and activity under temperature and stress extremes.
Claudia Wood +6 more
doaj +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source