Results 61 to 70 of about 187,838 (300)

NMR solution structure of a cold-adapted thiol-disulfide oxidoreductase [PDF]

, 2011
Psychrophilic enzymes produced by cold-adapted micro-organisms have successfully overcome the low temperature challenge and adapted to maintain high catalytic rates in their permanently cold environments.
Collins, Tony, Lamosa, Pedro, Matzapetakis, Manolis, Pais, Tiago, Santos, Helena   +4 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Outer membrane vesicles from cold-adapted antarctic bacteria [PDF]

, 2014
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/63704Many Gram-negative, cold-adapted bacteria from the Antarctic environment produce large amounts of extracellular matter with potential biotechnological applications.
Mercadé Gil, M. Elena, Pérez Cruz, Carla   +1 more
core  

Nonreceding hare lines: genetic continuity since the Late Pleistocene in European mountain hares (Lepus timidus) [PDF]

, 2017
Throughout time, climate changes have caused substantial rearrangements of habitats which have alternately promoted and disfavoured different types of taxa.
Dalén, L., Fladerer, F.A., Germonpré, M., Lagerholm, V. K., Miller, R., Napierala, H., Sablin, M., Sandoval-Castellanos, E., Smith, S., Stewart, John R., Von Seth, J., Wojtal, P.   +11 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Rational engineering of a cold-adapted α-amylase from the Antarctic ciliate Euplotes focardii for simultaneous improvement of thermostability and catalytic activity [PDF]

, 2017
The α-amylases are endo-acting enzyme which hydrolyze starch by randomly cleaving the 1,4-α-D-glucosidic linkages between the adjacent glucose units in linear amylose chain.
Ballarini, Patrizia, Miceli, Cristina, Mozzicafreddo, Matteo, Pucciarelli, Sandra, Yang, Guang, Yao, Hua   +5 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Establishment of a TaqMan-based real-time quantitative PCR method for detection of exogenous fowl adenovirus type Ⅰ, type Ⅲ and avian leukosis virus in human cold adapted live attenuated influenza vaccines

Heliyon, 2023
Cold adapted live attenuated influenza vaccines can effectively prevent human disease and death caused by influenza virus. Since chicken embryos are used as the culture substrate for the large-scale production of influenza vaccines, cold adapted live ...
Min Wu, Baihui Zhi, Rui Sheng, Entong Zhou, Qian Zhou, Jiemin Li, Xiaoshu Fu, Yanchun Wu, Yunchang Zhang, Pingjie Sun, Wei Jia, Liang Shi, Dawei Liu, Hui Zhao, Weiheng Su   +14 more
doaj   +1 more source

Adaptational properties and applications of cold-active lipase from psychrophilic bacteria [PDF]

, 2014
Psychrophilic microorganisms are cold-adapted with distinct properties from other thermal classes thriving in cold conditions in large areas of the earth's cold environment.
Leow, Thean Chor, Maiangwa, Jonathan, Mohamad Ali, Mohd Shukuri, Mohd Shariff, Fairolniza, Raja Abdul Rahman, Raja Noor Zaliha, Salleh, Abu Bakar   +5 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source