Results 71 to 80 of about 210,476 (300)

Identification and molecular characterization of a psychrophilic GH1 β-glucosidase from the subtropical soil microorganism Exiguobacterium sp. GXG2

AMB Express, 2019
The products of bacterial β-glucosidases with favorable cold-adapted properties have industrial applications. A psychrophilic β-glucosidase gene named bglG from subtropical soil microorganism Exiguobacterium sp.
Bangqiao Yin, Hengsen Gu, Xueyan Mo, Yue Xu, Bing Yan, Quanwen Li, Qian Ou, Bo Wu, Chen Guo, Chengjian Jiang   +9 more
doaj   +1 more source

07 Intern Assignment Biological Adaptations [PDF]

, 2020
WELCOME to WINDOWS on the INQUIRY CLASSROOM! You have landed on a piece of a National Science Foundation Project (DUE 1245730) directed by Professor Chris Bauer, Chemistry Department, University of New Hampshire.
Bauer, Christopher F.
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

High‐Spin States of Manganese(III) Enable Robust Cold‐Adapted Activity of MnO2 Nanozymes

Advanced Science
Developing novel cold‐adapted nanozymes and elucidating their mechanisms of action remains a great challenge. Inspired by natural oxidases that utilize high‐spin and high‐valent metal‐oxygen intermediates to achieve high efficiency at low temperatures ...
Qing Tian, Shuaiqi Huangfu, Ge Kang, Haoyu Wang, Huile Liu, Xuejing Wang, Aipeng Li, Yao Chen, Kelong Fan, Lianbing Zhang   +9 more
doaj   +1 more source

Origin of Life

, 2012
The evolution of life has been a big enigma despite rapid advancements in the fields of biochemistry, astrobiology, and astrophysics in recent years.
A. Gibbons, Ashwini Kumar Lal, C. Bohler, C. Chyba, C. Huber, C.E. Manning, C.J. Salter, D. Penny, D. Warmflash, D.S. Heckman, D.S. Mckay, E.G. Roussel, F. Hoyle, F. Hoyle, F. Hoyle, G.F. Joyce, H.C. Arp, H.C. Urey, J. Li, J. Maddox, J. Postgate, J.B.S. Haldane, J.K. Fredrickson, J.V. Narlikar, J.W. Schopf, K. Kvenvolden, L.-H. Lin, L.E. Orgel, L.J. Richardson, M.T. Mondigan, N.C. Wickramsinghe, P. David, P. Ehrenfreund, P. Senapathy, R. Shapiro, R.D. Lorenz, S Arrhenius, S.J. Mojzsis, S.L. Miller, S.L. Miller, Stofan, T. Brock, T.D. Brack, W. Gilbert, W. Martin, Y.-J. Kuan, Y.-J. Ma   +46 more
core   +1 more source

Single HA2 mutation increases the infectivity and immunogenicity of a live attenuated H5N1 intranasal influenza vaccine candidate lacking NS1 [PDF]

, 2011
Background: H5N1 influenza vaccines, including live intranasal, appear to be relatively less immunogenic compared to seasonal analogs. The main influenza virus surface glycoprotein hemagglutinin (HA) of highly pathogenic avian influenza viruses (HPAIV ...
Batishchev, Oleg V., Cinatl, Jindrich, Egorov, Andrej, Ferko, Boris, Geiler, Janina, Hinterdorfer, Peter, Humer, Johannes, Indenbom, Andrey V., Kastner, Markus, Kiefmann, Bettina, Kiselev, Oleg A., Krenn, Brigitte M., Michaelis, Martin, Morokutti, Alexander, Muster, Thomas, Nakowitsch, Sabine, Romanova, Julia, Romanovskaya-Romanko, Ekaterina, Ruthsatz, Tanja, Sturlan, Sanda, Wolschek, Markus, Wressnigg, Nina, Zhu, Rong   +22 more
core   +4 more sources

Cold-adapted enzymes produced by fungi from terrestrial and marine Antarctic environments [PDF]

Critical Reviews in Biotechnology, 2017
Antarctica is the coldest, windiest, and driest continent on Earth. In this sense, microorganisms that inhabit Antarctica environments have to be adapted to harsh conditions. Fungal strains affiliated with Ascomycota and Basidiomycota phyla have been recovered from terrestrial and marine Antarctic samples.
Alysson Wagner Fernandes Duarte, Juliana Aparecida dos Santos, Marina Vitti Vianna, Juliana Maíra Freitas Vieira, Vitor Hugo Mallagutti, Fabio José Inforsato, Lia Costa Pinto Wentzel, Luciana Daniela Lario, Andre Rodrigues, Fernando Carlos Pagnocca, Adalberto Pessoa Junior, Lara Durães Sette   +11 more
openaire   +3 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Cold-adapted protease enables quantitation of surface proteins in the absence of membrane trafficking

BioTechniques, 2017
Protocol Summary We report here an improved method for analyzing protein surface expression utilizing a cold-adapted trypsin. Preservation of activity of the enzyme at 0–4°C permits modification of the protease method of surface analysis to temperatures ...
Faraz Ahmad, Sarah Kate Coleman, Kai Kaila, Peter Blaesse   +3 more
doaj   +1 more source

Engineering low-temperature expression systems for heterologous production of cold-adapted enzymes [PDF]

Bioengineered, 2016
Production of psychrophilic enzymes in the commonly used mesophilic expression systems is hampered by low intrinsic stability of the recombinant enzymes at the optimal host growth temperatures. Unless strategies for low-temperature expression are advanced, research on psychrophilic enzymes may end up being biased toward those that can be stably ...
Bjerga, Gro Elin Kjæreng, Lale, Rahmi, Williamson, Adele Kim   +2 more
openaire   +4 more sources