Results 31 to 40 of about 380,192 (309)

New design of process for cold forging to improve multi-stage gas fitting

open access: yesAdvances in Mechanical Engineering, 2016
This work develops a process that solves the problem of the formation of cracks inside forged gas fittings in the cold forging process that arises from poor forging process design. DEFORM-3D forming software was utilized, and macroscopic experiments with
Han-Sung Huang, Shao-Yi Hsia
doaj   +1 more source

FE analysis of multi-cycle micro-forming through using closed-die upsetting models and forward extrusion models

open access: yes, 2007
Research in micro-forming leads to the investigation of the effects of heat generation in the workpiece and temperature changes in the tools during the forming.
Pan, Wenke, Qin, Yi, Pan, W., Qin, Y.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Development of thermocyclic processing modes for carbon steels used on cold forming tools

open access: yesE3S Web of Conferences, 2023
In this paper, the effect of thermocyclic processing regimes on carbon tool steels used in cold stamping tools is considered. Thermocyclic processing (TCP) is based on the idea of repeated heating-cooling of steels at a temperature different from conventional heating.
Ergashev D., Khudayberdiev O.
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Stochastic simulation of woven composites forming [PDF]

open access: yes, 1995
A stochastic forming simulation procedure is developed and implemented to investigate the effect of geometric variability in pre-impregnated woven textiles on manufacturing. Image analysis is used to characterise variability in tow directions and unit
Waal, de, H.   +5 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The influence of process parameters on the temperature development in the forming zone [PDF]

open access: yesMATEC Web of Conferences, 2018
Cold metal forming is a fast and economical way of producing a wide range of precise components. Its profitability mainly depends on part quality, process stability and service intervals of tools.
Tröber Philipp   +5 more
doaj   +1 more source

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