Results 31 to 40 of about 12,584,658 (247)

New design of process for cold forging to improve multi-stage gas fitting

Advances in Mechanical Engineering, 2016
This work develops a process that solves the problem of the formation of cracks inside forged gas fittings in the cold forging process that arises from poor forging process design. DEFORM-3D forming software was utilized, and macroscopic experiments with
Han-Sung Huang, Shao-Yi Hsia
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Integrated Process Simulation and Die Design in Sheet Metal Forming [PDF]

, 2007
During the recent 10-15 years, Computer Aided Process Planning and Die Design evolved as one of the most important engineering tools in sheet metal forming, particularly in the automotive industry. This emerging role is strongly emphasized by the rapid
Lukács, Zsolt, Tisza, Miklós, Gál, G.
core   +1 more source

Dimpling process in cold roll metal forming by finite element modelling and experimental validation

, 2014
The dimpling process is a novel cold-roll forming process that involves dimpling of a rolled flat strip prior to the roll forming operation. This is a process undertaken to enhance the material properties and subsequent products’ structural performance ...
Nguyen, Van Bac, M A English (16155080), English, Martin, Castellucci, Michael, M A Castellucci (16156652), Wang, Chang, V B Nguyen (16155074), Chang Wang (4464778), Mynors, Diane, D J Mynors (16155077)   +9 more
core   +1 more source

Mechanical Surface Treatment of Cold-Extruded Workpieces

, 2022
Cold-forming processes represent important technologies in steel processing. Cold-formed workpieces are often case-hardened in an energy- and cost-intensive process. Alternative finishing can be carried out by means of mechanical surface treatments, such
Tim Herrig, Herrig, Tim, Müller, Martina, Weiser, Ingo Felix, Thomas Bergs, Martina Müller, Ingo Felix Weiser, Herrmann, Peter, Bergs, Thomas, Peter Herrmann   +9 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

FEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim, Thi Thanh Mai Tran, Nakyung Kang, Min‐Woo Lee, Mihye Lee   +4 more
wiley   +1 more source

The influence of process parameters on the temperature development in the forming zone [PDF]

MATEC Web of Conferences, 2018
Cold metal forming is a fast and economical way of producing a wide range of precise components. Its profitability mainly depends on part quality, process stability and service intervals of tools.
Tröber Philipp, Welm Markus, Weiss Hannes Alois, Demmel Peter, Golle Roland, Volk Wolfram   +5 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source