Results 11 to 20 of about 4,070 (143)

Acepromazine Reduces Airway Contraction in a Murine Model of Asthma. [PDF]

Clin Exp Pharmacol Physiol
ABSTRACT Acepromazine (ACP) is one of the most used sedatives in veterinary medicine, and its cardiovascular effects are well documented. In contrast, its effects on the respiratory system remain less well understood, particularly in the context of assessment of respiratory mechanics in murine models of asthma, where its use has become more common in ...
Lino-Alvarado A, de Oliveira MA, Serra CSM, Melhado IVS, Campos R, Riffo-Vasquez Y, Moriya HT.   +6 more
europepmc   +2 more sources

Exacerbations and Management of Asthma in Viral Lower Respiratory Tract Infections: The Significance of Immunoglobulin E. [PDF]

Immun Inflamm Dis
ABSTRACT Background Viral‐respiratory infections are the most prevalent illness among humans. A viral infection affecting lower respiratory tract infections (LRTI) is a critical health concern worldwide. The COVID‐19 pandemic has significantly impacted respiratory health, particularly in individuals with asthma.
Akhavan M, Yousefi P, Tabibzadeh A.
europepmc   +2 more sources

Natural History of Airway Hyperresponsiveness and Its Association With Asthma Traits. [PDF]

Allergy
AHR improves in most children over adolescence when its relationship with asthma changes. AHR is better at ruling out asthma in children, while it is superior at ruling in asthma in young adults. Age should be considered when interpreting AHR, and different cutoffs might be required for children and adults.
Carra S, Zhang H, Kurukulaaratchy RJ, Arshad SH.   +3 more
europepmc   +2 more sources

Bronchial inflammatory profile in interferon-gamma-mediated immune response in asthma patients during airway response to cold stimulus

Frigid Zone Medicine, 2022
To evaluate the inflammatory pattern and the interferon (IFN)-γ in the bronchial secretion of asthma patients in response to acute cold bronchoprovocation.
Perelman Juliy M., Pirogov Aleksey B., Prikhodko Anna G., Kolosov Victor P.   +3 more
doaj   +1 more source

Specific features of bronchial inflammation in asthma patients with airway hyper-responsiveness to cold and osmotic stimuli

Бюллетень сибирской медицины, 2017
Background. Excessive airway reaction to combined effects of environmental factors is very common in patients with asthma. The understanding of the molecular-cellular mechanisms of this hyperresponsiveness is very important.Aim.
Aleksey B. Pirogov, Anna G. Prikhodko, Sergey V. Zinov’ev, Eugen A. Borodin, Elena V. Ushakova, Galina A. Makarova, Juliy M. Perelman   +6 more
doaj   +1 more source

TRPM8 is overexpressed in the respiratory tract of steroid-naive asthma patients

Asian Pacific Journal of Tropical Medicine, 2018
Background: TRPM8 is a member of TRP channels family known for its sensitivity to cool temperature, increased osmotic pressure, particulate matter, cigarette smoke and products of oxidative stress.
Denis Naumov, Dina Gassan, Kseniya Kilimichenko, Evgeniya Afanaseva, Elizaveta Sheludko, Victor Kolosov, Xiang-dong Zhou   +6 more
doaj   +1 more source

ROLE OF TRPM8 GENE POLYMORPHISMS IN THE FORMATION OF ASTHMA PHENOTYPE WITH COLD AIRWAY HYPERRESPONSIVENESS

Bulletin physiology and pathology of respiration, 2017
The aim of the study was to evaluate the effect of TRPM8 cold thermoreceptor gene polymorphisms on the development of asthma phenotype with cold airway hyperresponsiveness (CAH). 167 cases of mild-to-moderate persistent asthma were retrospectively analyzed. In each case, the examination included two repeated bronchoprovocation tests with 3-min isocapic
Viktor Kolosov, Yuliy Perelman, Anna Prikhodko, Dina Gassan, Olesya Kotova, Denis Naumov   +5 more
openaire   +4 more sources

Acute Exercise Challenge and Airway Dynamics in Youth With Sickle Cell Anemia: A Multicenter Study. [PDF]

Am J Hematol
Changes in airway dynamics in children with sickle cell anemia after maximal cardiopulmonary exercise testing and a controlled intensity interval excercise challenge. ABSTRACT Sickle cell anemia (SCA) leads to reduced physical functioning and cardiopulmonary fitness. Prior studies suggest that airway hyperresponsiveness to bronchoprovocation testing is
Cohen RT, Hankins JS, Ness KK, Hsu LL, Baynard T, Tang A, Radom-Aizik S, Guerrero K, Rodeghier M, Liem RI.   +9 more
europepmc   +2 more sources

The Influence of Cold Atmospheric Air on the Environmental Health of Sportsman

Людина і довкілля: Проблеми неоекології, 2019
On the basis of a systematic analysis of the scientific literature, it was found that the increased sensitivity of a modern human being to the negative effects of the cold natural environment is due to its passage from the shrouds of East Africa with ...
O. I. Tsyganenko, I. M. Khomenko, Ya. V. Pershehuba, L. M. Avramenko, N. A. Sklyarova   +4 more
doaj   +1 more source

The influence of smoking on the formation of airway hyperresponsiveness to cold and the course of destructive-cytological processes in the goblet cells of the bronchial epithelium in patients with asthma

Бюллетень сибирской медицины, 2019
Tobacco smoking in patients with asthma can intensify the bronchi mucosa damage and significantly worsen the course of the disease.Aim. To assess the influence of tobacco smoking on the clinical manifestations of the disease, airway response to cold air ...
A. B. Pirogov, A. G. Prikhodko, V. P. Kolosov, Ju. M. Perelman   +3 more
doaj   +1 more source