Results 121 to 130 of about 3,544,105 (247)

Integrated Multiomic Analysis Reveals an EBV‐Associated MIF–SPP1+ Macrophage Axis Linking Tumor Stemness and Immune Dysfunction in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study maps how Epstein–Barr virus reshapes the cellular ecosystem of nasopharyngeal carcinoma. It identifies SPP1+ macrophages as partners of stemness‐associated tumor cells and dysfunctional T cells, links tumor‐derived MIF to macrophage recruitment and programming, and shows that macrophage‐derived SPP1 promotes tumorsphere formation and impairs
Guo‐Ying Liu, Shu‐Hui Lv, Shui‐Qing He, Yao‐Fei Jiang, Xing‐Si Peng, Jian‐Cong Sun, Fen He, Hai‐Yan Qin, Nian Lu, Wei‐Xin Bei, Lin‐Yu Zhao, Wan‐Qin Shen, Ze‐Yu Zhao, Lin Wang, Yan‐Qun Xiang, Wang‐Zhong Li   +15 more
wiley   +1 more source

Role of Plasma Surface Treatments on Wetting and Adhesion

, 2009
There are many current and emerging wetting and adhesion issues which require an additional surface processing to enhance interfacial surface properties.
Sparavigna, Amelia Carolina, Wolf R., Rory Wolf, Wolf, R., Amelia Carolina Sparavigna   +4 more
core   +1 more source

Integrated Single‐Cell and Spatial Transcriptomics Reveal Convergence on a Senescence‐Associated B Cell–MIF Signaling Axis in Joint Aging and Osteoarthritis Progression

Advanced Science, EarlyView.
Single‐cell and spatial transcriptomics implicate senescent B cells and macrophage migration inhibitory factor (MIF) signaling in aging and osteoarthritic joints. An injectable hydrogel combining quercetin with siRNA targeting MIF attenuates cartilage degeneration in a mouse model of osteoarthritis.
Weida Li, Yi Wang, Yongqing You, Yue Cui, Jiayun Liu, Xingbiao Ma, QiuYu Zhu, Qiang Wu, Zanjing Zhai, Zuyan Lu, Kerong Dai, Ye Sun   +11 more
wiley   +1 more source

Negative Gauge Factor Piezoresistance in Soft Strain and Pressure Sensors: Mechanisms, Materials, and Emerging Applications

Advanced Science, EarlyView.
Negative‐gauge‐factor materials reverse the usual rule of piezoresistive sensing: their resistance falls, rather than rises, under deformation. This review organizes such behavior into four mechanistic classes spanning intrinsic semiconductors, composites, conducting polymers, and engineered architectures.
Su‐Hyeong Lee, Minjae Kim, Soosang Chae   +2 more
wiley   +1 more source

FADS2‐STING Signaling in Sertoli Cells Orchestrates Collagen Deposition and Germ Cell Necroptosis in Idiopathic Non‐Obstructive Azoospermia

Advanced Science, EarlyView.
In Sertoli cells of iNOA testes, downregulation of FADS2 activates STING, promoting collagen deposition and peritubular fibrosis while increasing germ‐cell susceptibility to necroptosis. Supplementation with FADS2‐derived PUFAs (GLA and DHA) inhibits STING, alleviates collagen accumulation, and facilitates the recovery of spermatogenesis.
Jiajing Lin, Hongfei Ke, Xiaomin Li, Man Wu, Zhengyan Wu, Zhiying Huang, Feixue Han, Dejian Pang, Shuyan Chen, Tianwen Peng, Yu Lan, Xin Fu, Yingying Zhang, Hyeon Jeong Lee, Zhicong Chen, Geng An   +15 more
wiley   +1 more source

The Effect of an Atmospheric Plasma Source on Blood Coagulation

, 2019
Plasma medicine is an emerging field among the broad spectrum of plasma science applications. It deals with the use of cold plasmas produced at atmospheric pressure in order to obtain a therapeutic effect on living matter.
Cavazzana R, Scalise M, Martines E, Tammè L, De Masi G, Cordaro L, Fassina A, Zaniol B, De Rosa S, Marinaro G, Gareri C, Zuin M, Indolfi C, Brun P   +13 more
core  

Post‐Synthetic Cerium Modification of Commercial NCM811 for Concurrent Cycling and Safety Upgrading

Advanced Science, EarlyView.
Cerium ion doping and CeO2 coating work synergistically to reinforce commercial NCM811 cathodes. This strategy stabilizes the lattice and strengthens the interface against degradation and side reactions. The modified cathode shows enhanced rate capability and cycling stability.
Wei‐Wei Wang, Da‐Kun Chen, Wei Kang, Xiao‐Mei Wu, Qing Cao, Quan‐Fang Wang, Si‐Yuan Ma, Hai‐Long Wang, Jing‐Hua Tian, Zhong‐Qun Tian   +9 more
wiley   +1 more source

Synthesis Route‐Controlled Atomic Ordering Optimizes Thermoelectric Transport in Bi2SbSe3

Advanced Science, EarlyView.
Atomic ordering modulation enhancing the thermoelectric performance of Bi2SbSe3. The solid‐state synthesis route redistributes Sb atoms between the Bi2Se3 quintuple layers and the Bi bilayers in the BiSe structure, resulting in a more disordered Bi2SbSe3 than the one‐pot synthesized counterpart.
Xiaoqian Wang, Shulin Bai, Huiqiang Liang, Rong Liu, Chao Liang, Yiqing Jia, Xiaokun Feng, Zhengguo Bai, Tian Gao, Huixin Pang, Yongjin Chen, Xin Qian, Zilu Wang, Haonan Shi, Sining Wang, Yi Wen, Peikang Bai, Lizhong Su, Li‐Dong Zhao   +18 more
wiley   +1 more source

A Bioengineered Mitochondrial Respiration‐Mimetic Copper‐Based Metal‐Organic Framework Reprogramming Oxidative Phosphorylation to Enhance Tumor Cuproptosis

Advanced Science, EarlyView.
A bioengineered mitochondrial respiration‐mimetic nanoplatform (TC@OMG) renews tumor mitochondrial metabolism to enhance cuproptosis. TC@OMG integrates a copper‐based metal‐organic framework co‐loaded with glucose oxidase and a lactate dehydrogenase inhibitor, and is cloaked with a hybrid membrane derived from tumor cells and plant thylakoids, enabling
Liyang Zhou, Hongpei Deng, Tingli Zheng, Huan Min, Qiwei Tian, Huimin Lin, Jing Ruan, Xianqun Fan   +7 more
wiley   +1 more source

Localized Hydrogen Release Driven by Mg–Pd Microgalvanic Cells from 3D‐Printed Microneedles Reverses Redox Homeostasis for Psoriasis Treatment

Advanced Science, EarlyView.
A 3D printing microneedle (MP‐MN), loading magnesium‐based micro‐galvanic cells (MP), is designed for improving psoriasis. H2 generated from MP‐MN scavenges ROS and •OH, actives NRF2‐KEAP1 pathway, and decreases inflammation, thereby effectively restoring the oxidative stress homeostasis of psoriatic skin and suppressing the excessive proliferation of ...
Xinyue Shao, Zongyan He, Ning Yang, Lixuan Yin, Xujie Sun, Jingtong Qi, Xiaolong Feng, Yihui Zhang, Yiran Liu, Zhengwei Huang, Tianqun Lang   +10 more
wiley   +1 more source