Results 191 to 200 of about 9,593 (250)

Surface Micro‐Discharge Plasma for Multiple Teeth Bleaching: Efficacy, Mechanism and Safety

High Voltage, EarlyView.
ABSTRACT Hydrogen peroxide (H2O2) is the commonly‐used bleaching chemical in clinical practice, but its excessive concentrations can cause tooth damage. Atmospheric pressure cold plasma is considered a promising new technique for tooth bleaching. Surface micro‐discharge (SMD) devices can generate large‐scale plasma, which holds potential for treating ...
Ruike Chen, Haoran Feng, Yinglong Li, Hong Pan, Hangbo Xu, Zhen Jiao, Dongjie Cui, Ruonan Ma   +7 more
wiley   +1 more source

Study on the Power‐Frequency Arc Extinction Characteristics of Semi‐Closed Short‐Gap Device

High Voltage, EarlyView.
ABSTRACT Multi‐chamber arc‐extinguishing devices have a simple structure and excellent arc‐extinguishing performance; thus, they have attracted considerable attention as lightning protection devices. However, the structural parameters of different models of the aforementioned devices vary, leading to inconsistent protection levels; therefore, the arc ...
Yeqiang Deng, Caiwei Pan, Jintian Chen, Yu Wang, Lei Lan   +4 more
wiley   +1 more source

Umbilical Cord Blood–Derived Extracellular Vesicles Enhance Neurovascular Regeneration and Improve Erectile Function in a Mouse Model of Bilateral Cavernous Nerve Injury

Andrology, EarlyView.
ABSTRACT Background Erectile dysfunction (ED) secondary to cavernous nerve injury (CNI), such as that occurring after radical prostatectomy, remains a significant clinical challenge, particularly among patients who do not respond to phosphodiesterase Type 5 inhibitors (PDE5i).
Minh Nhat Vo, Guo Nan Yin, Fitri Rahma Fridayana, Yan Huang, Limanjaya Anita, Ju‐Hee Kang, Ji‐Kan Ryu   +6 more
wiley   +1 more source

Prevention and Management of Driveline Infections in Ventricular Assist Device Patients: The DESTINE 2.0 Staging Proposal and Expert Recommendations

Artificial Organs, EarlyView.
DESTINE 2.0 decision flowchart: stage‐based assessment and management of driveline exit‐site disorders. The flowchart provides a simplified decision‐support tool for the stage‐based evaluation and management of driveline exit‐site disorders in LVAD patients, intended as a practical complement to the staging pyramid (Figre 2) and the detailed staging ...
Alexander M. Bernhardt, Volker Lauenroth, Florian Mueller, Friedrich Kaufmann, Katharina Homann, Martina Socha, Thomas Schlöglhofer, the Driveline Expert STagINg and carE (DESTINE) study group   +7 more
wiley   +1 more source

Direct evidence implicating the asymmetrical dimethylarginine (ADMA)‐dimethylarginine dimethylaminohydrolase 1 (DDAH1) pathway in cerebrovascular dysfunction and stroke pathogenesis in mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Asymmetrical dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase (NOS), whereas dimethylaminohydrolase 1 (DDAH1) is primarily responsible for its metabolism. However, the roles of DDAH1 in cerebrovascular regulation are poorly understood. Furthermore, despite evidence that elevated ADMA levels are
Arun Flynn, Alexandra Riddell, Ashton Bernard, Jennifer Haggarty, Stefan Weidt, Jawza Alenazi, Erika Trabold, Delyth Graham, Laura B. Dowsett, James Leiper, Alyson A. Miller   +10 more
wiley   +1 more source

Physiological media and oxygen levels modulate cancer hallmarks in cultured breast cancer cells

The FEBS Journal, EarlyView.
MCF7 breast cancer cells were cultured in standard conditions (18% O2 and DMEM) and physiological conditions (5% O2 and Plasmax, a medium modeled after the human plasma metabolome). A combined transcriptomic and proteomic approach was used to identify gene expression signatures at the mRNA and protein levels upstream of functional enrichment analyses ...
Jacob E. Wiebe, Ricardo Alva, Fereshteh Moradi, Sarah Alderman, Ping Liang, Jeffrey A. Stuart   +5 more
wiley   +1 more source

Plasma Disinfection: Cold Atmospheric Pressure Plasma Attenuates SARS-CoV-2 Spike Protein Binding to ACE2 Protein and the RNA

, 2021
Khanikar RR, Kalita M, Kalita P, Kashyap B, Das S, Khan MR, Bailung H, Sankaranarayanan K.   +7 more
europepmc   +1 more source

Metabolic Profiling of Circulating and Tumour‐Infiltrating T Cells Uncovers Bioenergetic Checkpoints Linked With Immune and Clinical Skewing in Melanoma Patients

Immunology, EarlyView.
In this study, we revealed the disturbed metabolic status of circulating and tumour‐infiltrating CD4+ and CD8+ T cells in melanoma patients through targeted metabolomic and lipidomic (on sorted subsets) and at single cell level using the SCENITH method.
Hugo Brouque, Kareem Mahdy, Stephane Mouret, Sylvain Henry, Camille Niveau, Mélanie Cettour‐Cave, Martin Pelosse, Florence de Fraipont, Julie Charles, Andrei Turtoi, Philippe Saas, Caroline Aspord   +11 more
wiley   +1 more source

Linoleic Acid Enhances Murine Natural Killer Cell Function In Vitro but Compromises Mitochondrial Bioenergetic Function During Retroviral Infection

Immunology, EarlyView.
Natural Killer (NK) cells are potent effectors against virus‐infected and tumour cells. During Friend Virus (FV) infection, fatty acid metabolism supports NK‐cell effector functions. Here, we found that NK cells from FV‐infected mice preferentially take up linoleic acid (LA), which reduced proliferation, mitochondrial function, and increased reactive ...
Vaasudevan Sridhar, Simone Schimmer, Tanja Werner, Rachel Giesen, Mohamed Saad, Constantin P. Krempe, Sven W. Meckelmann, Ulf Dittmer, Elisabeth Littwitz‐Salomon   +8 more
wiley   +1 more source

Marine migration influences mercury accumulation in anadromous Arctic char (Salvelinus alpinus)

Journal of Fish Biology, EarlyView.
Abstract Mercury (Hg) is a globally distributed toxic metal present in northern natural environments that biomagnifies in food webs and bioaccumulates in apex predator fish, such as Arctic char (Salvelinus alpinus)—an iteroparous species with a circumpolar distribution. Arctic char exhibit a variety of life history types, with the migrating, anadromous
Isabel R. Hilgendag, Michael Power, Mehdi M. Aqdam, Christopher W. Lewis, Zoya Martin, Ashley D. Ehrman, Heidi K. Swanson   +6 more
wiley   +1 more source