Results 21 to 30 of about 966,468 (273)

Minimizing the source of nociception and its concurrent effect on sensory hypersensitivity: An exploratory study in chronic whiplash patients [PDF]

open access: yesBMC Musculoskeletal Disorders, 2010
Background The cervical zygapophyseal joints may be a primary source of pain in up to 60% of individuals with chronic whiplash associated disorders (WAD) and may be a contributing factor for peripheral and centrally mediated pain (sensory ...
Stratford Paul   +7 more
doaj   +3 more sources

Herbal Medicines for Cold Hypersensitivity in the Hands and Feet: A Systematic Review and Meta-Analysis [PDF]

open access: yesJournal of Alternative and Complementary Medicine, 2018
Sei Jin Chang   +2 more
exaly   +2 more sources

Efficacy of two commercially available dentifrices in reducing dentinal hypersensitivity

open access: yesIndian Journal of Dental Research, 2010
Objective: A parallel design clinical study evaluated reduction in hypersensitivity after brushing for 12 weeks with Anchor toothpaste (containing potassium citrate, zinc citrate, triclosan and sodium monofluorophosphate) (test) and Colgate Total (sodium
Prasad KVV   +5 more
doaj   +1 more source

hnRNPA1 SUMOylation promotes cold hypersensitivity in chronic inflammatory pain by stabilizing TRPA1 mRNA

open access: yesCell Reports, 2023
Summary: TRPA1 is pivotal in cold hypersensitivity, but its regulatory mechanisms in inflammatory cold hyperalgesia remain poorly understood. We show here that the upregulation of SUMO1-conjugated protein levels in a complete Freund’s adjuvant (CFA ...
Qiao Zhang   +8 more
doaj   +1 more source

Plant derived aporphinic alkaloid S-(+)-dicentrine induces antinociceptive effect in both acute and chronic inflammatory pain models: evidence for a role of TRPA1 channels. [PDF]

open access: yesPLoS ONE, 2013
S-(+)-dicentrine is an aporphinic alkaloid found in several plant species, mainly from Lauraceae family, which showed significant antinociceptive activity in an acute model of visceral pain in mice.
Deise Prehs Montrucchio   +2 more
doaj   +1 more source

Clinical Evaluation of Pro-Argin and Low Level Laser Therapy in the Treatment of Dentinal Hypersensitivity: A Splitmouth Randomised Clinical Trial [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2023
Introduction: Dentinal Hypersensitivity (DH) is the most prevalent condition that causes patients discomfort for patients, leading them to frequently visit dental offices.
B Anusha   +5 more
doaj   +1 more source

Prospective genetic screening decreases the incidence of Abacavir hypersensitivity reactions in the Western Australian HIV cohort study [PDF]

open access: yes, 2005
Abacavir therapy is associated with significant drug hypersensitivity in ∼8% of recipients, with retrospective studies indicating a strong genetic association with the HLA-B*5701 allelle.
McKinnon, E.   +11 more
core   +2 more sources

Mechanistic Differences in Neuropathic Pain Modalities Revealed by Correlating Behavior with Global Expression Profiling

open access: yesCell Reports, 2018
Summary: Chronic neuropathic pain is a major morbidity of neural injury, yet its mechanisms are incompletely understood. Hypersensitivity to previously non-noxious stimuli (allodynia) is a common symptom.
Enrique J. Cobos   +21 more
doaj   +1 more source

Oxaliplatin administration increases expression of the voltage-dependent calcium channel α2δ-1 subunit in the rat spinal cord

open access: yesJournal of Pharmacological Sciences, 2016
Oxaliplatin is a chemotherapeutic agent that is effective against various types of cancer including colorectal cancer. Acute cold hyperalgesia is a serious side effect of oxaliplatin treatment.
Ken Yamamoto   +7 more
doaj   +1 more source

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