Results 91 to 100 of about 3,566,597 (273)

Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency

Advanced Materials, EarlyView.
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang, Jerry Leung, Judy Cheng, Arash Momeni, Albert Kamanzi, Ariadne Tuckmantel Bido, Suiyang Liao, Emma Kang, Colton Strong, Christian J. Kastrup, Sabrina Leslie, Miffy Hok Yan Cheng, Pieter R. Cullis   +12 more
wiley   +1 more source

Development of Turbulence in Postshock Regions

The Astrophysical Journal
Supersonic isothermal turbulence is ubiquitous in the interstellar medium. This work presents high-resolution A REPO hydrodynamical simulations of isolated shocks moving through supersonic turbulence to study the development and evolution of turbulence ...
Michael M. Foley, Philip Mocz, Blakesley Burkhart, Lars Hernquist, Alyssa Goodman   +4 more
doaj   +1 more source

In Situ Formation of a Highly Selective Nickel Single Atom Catalyst for Electrochemical CO2 Reduction to CO

Advanced Materials, EarlyView.
Development of a novel method for synthesizing Ni single atom catalysts for highly selective electrochemical CO2 reduction in situ. This catalyst achieves 100% selectivity for CO and is formed in an industrially relevant cell architecture. Using post‐mortem XRD, STEM, and EDS and operando XAS, the identity of the active site and the mechanism behind ...
Ian Street, Venkata Sai Sriram Mosali, Noah Sandberg, Fengyuan Shi, Deborah Myers, William E. Mustain   +5 more
wiley   +1 more source

The effects of hyperoxia on exercise performance in the cold [PDF]

, 2017
This study tested whether hyperoxia improves exercise performance in moderately-cooled individuals, along with the relationship between cold and hyperoxia on cerebral and muscle oxygenation as potential mechanisms for improvement.
Ferguson, Steven
core   +1 more source

Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy

Advanced Materials, EarlyView.
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo, Min Ge, Zesong Ruan, Tingwang Shi, Mahyar Mahmoudi, Soohwan An, Na Kong, Yunfeng Chen, Han Lin, Wei Tao   +9 more
wiley   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Extraction and process optimization of East Indian Red Wood (Caesalpinia sappan) in stirred yoghurt

Madras Agricultural Journal
Yoghurt is a fermented dairy product, having several health benefits. Redwood sappan wood (Caesalpinia sappan) is a plant yielding bark and stem with water soluble red pigment. Two methods of colour extraction were carried out, namely, Heat Extraction
P. Geetha, M. Esther Magdalene Sharon
doaj   +1 more source

Vitamin C‐Induced Photo‐Redox Threshold Enables High‐Fidelity Volumetric Printing of Collagen

Advanced Materials, EarlyView.
Tomographic volumetric printing (TVP) of native proteins is limited by uncontrolled background crosslinking. Here, vitamin C is introduced as a biocompatible redox regulator to establish a tunable nonlinear polymerization threshold response for TVP.
Bin Wang, Amelia Hasenauer, Kristian Ivkovic, Ann‐Sophie Frind, David Fercher, Marcy Zenobi‐Wong   +5 more
wiley   +1 more source

Quantification of Magnetic Interactions in van der Waals Heterostructures Using Lorentz Transmission Electron Microscopy and Off‐Axis Electron Holography

Advanced Materials, EarlyView.
Cross‐sectional Lorentz TEM and off‐axis electron holography visualize the magnetic domain structure and quantify interlayer coupling in Fe3GeTe2/graphite/Fe3GeTe2 heterostructures. A stray‐field coupling length of 37±$\pm$7 nm marks the onset of domain misalignment between the layers.
Joachim Dahl Thomsen, Qianqian Lan, Nikolai S. Kiselev, Eva Duft, Arslan Rehmat, Zdeněk Sofer, Rafal E. Dunin‐Borkowski   +6 more
wiley   +1 more source

Extragalactic Magnetism with SOFIA (SALSA Legacy Program). VII. A Tomographic View of Far-infrared and Radio Polarimetric Observations through MHD Simulations of Galaxies

The Astrophysical Journal
The structure of magnetic fields in galaxies remains poorly constrained, despite the importance of magnetism in the evolution of galaxies. Radio synchrotron and far-infrared (FIR) polarization and polarimetric observations are the best methods to measure
Sergio Martin-Alvarez, Enrique Lopez-Rodriguez, Tara Dacunha, Susan E. Clark, Alejandro S. Borlaff, Rainer Beck, Francisco Rodríguez Montero, Seoyoung L. Jung, Julien Devriendt, Adrianne Slyz, Julia Christine Roman-Duval, Evangelia Ntormousi, Mehrnoosh Tahani, Kandaswamy Subramanian, Daniel A. Dale, Pamela M. Marcum, Konstantinos Tassis, Ignacio del Moral-Castro, Le Ngoc Tram, Matt J. Jarvis   +19 more
doaj   +1 more source