Results 131 to 140 of about 162,200 (291)

Cold preservation with HPG solution maintains intracellular ATP pool in cultured HUVECs at 4°C.

open access: yes, 2015
Cold preservation with HPG solution maintains intracellular ATP pool in cultured HUVECs at 4°C.
Qiunong Guan (694937)   +6 more
core   +1 more source

Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl‐tRNA Synthetase Boosts Genetic Code Expansion in E. coli

open access: yesAdvanced Science, EarlyView.
ABSTRACT Orthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion. Current engineering strategies typically rely on hyperstable aminoacyl tRNA synthetase (aaRS) scaffolds to tolerate destabilizing mutations required for substrate diversification.
Nikolaj G. Koch   +4 more
wiley   +1 more source

Topographic Influence on Cold-Air Pool Formation: A Case Study of the Eiras Valley (Coimbra, Portugal)

open access: yesAtmosphere
Topography plays a crucial role in shaping local urban microclimates and can drive the formation of cold-air pools in valley bottoms. This study examines the Eiras Valley (Coimbra, Portugal), a rapidly growing peri-urban area, to identify the conditions ...
António Rochette Cordeiro   +2 more
doaj   +1 more source

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

open access: yesAdvanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su   +10 more
wiley   +1 more source

The Effect of Cold Pool Variability on Zooplankton Dynamics of the Eastern Bering Sea Shelf

open access: yes, 2020
Interannual variability of ocean temperatures and sea ice extent has been observed on the eastern Bering Sea (EBS) shelf, where annual conditions have resulted in regional “Cold” or “Warm” years.
Johnson, Jennifer J’Lai   +1 more
core  

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

open access: yesAdvanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou   +22 more
wiley   +1 more source

Tall tower observations of a northward surging gust front in central Amazon and its role in the mesoscale transport of carbon dioxide

open access: yesMeteorological Applications
High‐frequency measurements obtained at two micrometeorological towers are investigated for a rare northward surging gust front that impacted the Amazon Tall Tower Observatory (ATTO), in central Amazon. The gust front originated from a decaying mesoscale
Luciane I. Reis   +10 more
doaj   +1 more source

Convective memory, and the role of cold pools

open access: yes
La mémoire de la convection et le rôle des poches froides Les paramétrisations représentent encore mal la variabilité spatio-temporelle de la convection. Cela peut provenir du fait qu’elles supposent que la convection peut être diagnostiquée à partir des conditions de grande échelle. La mémoire de la convection, traduisant la dépendance
openaire   +3 more sources

Cold‐air pool development in a small Alpine valley

open access: yesQuarterly Journal of the Royal Meteorological Society
A field campaign in a valley near Seefeld, Austria, well known for the frequent occurrence of cold‐air pools, was conducted to identify the processes leading to the formation and erosion of the cold‐air pool. Here, we focus on a case study in January 2020 that featured cold‐air pool formation interrupted by a wind disturbance.
Andreas Rauchöcker   +3 more
openaire   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao   +11 more
wiley   +1 more source

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