Results 91 to 100 of about 1,177,497 (301)

Temporal Trajectories of the Tau Aggregate Interactome Reveal Stage‐Specific Vulnerabilities in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Tau populations with different aggregation states associate with distinct sets of proteins in the Alzheimer's disease brain. Proteomic discovery combined with single‐molecule analysis in neurons reveals dynamic associations involving proteostasis, metabolism and RNA biology.
Dorothea Böken   +8 more
wiley   +1 more source

Interface enhancement mechanism of rolled Mg/Al clad plate with particle interface control

open access: yesJournal of Magnesium and Alloys
In this study, the cold-spraying process was utilized to deposit Al particles onto an Al slab, an Mg slab, and both Al and Mg slabs to form an ultra-thin interlayer, and then the clad slabs were rolled at 400 °C, developing three roll-bonding processes ...
Xiaobao Ma   +5 more
doaj   +1 more source

Printing‐Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling

open access: yesAdvanced Science, EarlyView.
Extrusion‐based 3D printing of silicones and discrete electronic components are combined to create cortical implants for rodents that integrate thermal neuromodulation and electrical recording. Linked to an autonomous auxiliary driver unit, the system enables rapid, stable and localized hypothermia alongside ECoG recording.
Spencer Ryan Moore   +6 more
wiley   +1 more source

Cold spraying superalloys:research status,challenges and perspectives

open access: yesCailiao gongcheng
Cold spraying technology has a number of unique characteristics, most notably the solid-state metal powder deposition. This property confers the technology with significant technical advantages and application potentials in the domains of coating ...
LI Wenya   +7 more
doaj   +1 more source

Research Progress on Surface Strengthening and Repair Technologies for CuCrZr Alloys Used in Continuous-Casting Molds [PDF]

open access: yesCailiao Baohu
Continuous casting is a core process in China’ s steel industry. In 2024,China’ s crude steel output accounted for 53.3% of the global total. As the “heart” of continuous-casting equipment,the mold’ s service life directly constrains production ...
FU Wei, WANG Haopeng, LI Bo
doaj   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

open access: yesAdvanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li   +12 more
wiley   +1 more source

Nozzle optimization for cold gas dynamic spraying

open access: yesАвіаційно-космічна техніка та технологія
This study investigates the influence of nozzle geometry on the characteristics of the cold gas dynamic spraying (CGDS) process under low-pressure conditions (up to 1.0 MPa).
Oleksandr Shorinov   +3 more
doaj   +1 more source

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