Results 81 to 90 of about 1,177,497 (301)

SURFACE REPAIR OF AIRCRAFT TITANIUM ALLOY PARTS BY COLD SPRAYING TECHNOLOGY

open access: yesАвіаційно-космічна техніка та технологія, 2020
Titanium alloys have the advantages of high specific strength, good corrosion resistance, high heat resistance, and low density, which is the main structural material of aerospace system components, including compressor blade, cartridge receiver, blisk ...
Wenjie Hu   +4 more
doaj   +1 more source

Numerical Simulation of Hydroxyapatite Particle Impacting on Ti Substrate in Cold Spraying

open access: yes, 2011
Hydroxyapatite (HA) is a calcium phosphate ceramics and HA coating is essential for the medical metallic implants. This paper presents a computational model of HA particle impact behavior in cold spraying.
Wen Tao Zhang, Lei Zhang, Zhi Yong Wu
core   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

open access: yesAdvanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang   +11 more
wiley   +1 more source

Natural Product Toosendanin Suppresses the Malignant Development of Skin Melanoma by Targeting BNC2 for Degradation

open access: yesAdvanced Science, EarlyView.
BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai   +7 more
wiley   +1 more source

Method for Cold Gas Spraying

open access: yes, 2014
PatentschriftThe invention relates to a method for cold gas spraying in which a spray powder containing photocatalytically active spray particles is accelerated by means of a carrier gas in a nozzle and forms a coating upon striking a substrate ...
Gärtner, Frank   +6 more
core   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

open access: yesAdvanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao   +20 more
wiley   +1 more source

Sex‐ and Time‐Resolved Physiological and Gut Ecosystem Responses to a Food‐Grade Microbiome‐Targeted Intervention in Collegiate Endurance Athletes

open access: yesAdvanced Science, EarlyView.
In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang   +8 more
wiley   +1 more source

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