Results 71 to 80 of about 2,316,496 (284)
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Advances in Mechanical Engineering, 2017 Phase change material cold storage system could improve the efficiency and stability of the solar-powered air-conditioning system and the building thermal environment.
Lin Zheng, Wei Zhang, Fei Liang
doaj +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Sodium Formate as Low Temperature Phase Change Material in Cold Storage Insulation Box
Zhileng xuebao, 2017 The cold storage material of HCOONa?2H2O 21%+water 79% which have appropriate phase change temperature, large latent heat, large thermal conductivity and good stability was studied in this paper. Cold storage insulation boxes with two kinds of insulation
Chen Wenpu +4 more
doaj
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Apple storage in ultra-low oxygen cold store
International Journal of Agricultural Research, Innovation and Technology, 2019 Apple storage under lower concentration of oxygen (1.0-1.3% in some cases lower than 1%) in controlled atmosphere cold stores is described as apple storage in ultra-low oxygen cold store.
Ahmad Khasrow Afif
doaj +1 more source
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Shipin gongye ke-jiSweet corn was highly susceptible to senescence due to its elevated physiological metabolism after harvest, resulting in a decline in its edible quality.
Minmin SUN +5 more
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Improvement of the Cold Storage of Isolated Human Hepatocytes
Cell Transplantation, 2012 Increasing amounts of human hepatocytes are needed for clinical applications and different fields of research, such as cell transplantation, bioartificial liver support, and pharmacological testing.
Gesine Pless +2 more
doaj +1 more source
Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani +10 more
wiley +1 more source