Results 121 to 130 of about 40,088 (283)

Vorinostat Potentiates Chemoimmunotherapy in Immune‐Enriched Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Immune‐enriched pancreatic cancer does not confer a significant survival advantage. SAHA sensitizes these “hot” tumors to chemoimmunotherapy by disrupting a FASN/PARP9‐driven “metabolic trap” and enhancing CD8+ T cell function. A CD8high/FASNhigh/PARP9high signature identifies patients who are most likely to benefit from the “gemcitabine‐nivolumab‐SAHA”
Chen Chen   +13 more
wiley   +1 more source

CFD model of PWR reactor for cold plumes stratification study

open access: yes, 2017
Diplomová práce "CFD model reaktoru VVER-440 pro studium tlakově-teplotních šoků" se zaměřuje na popis havárií jaderných elektráren typu doprovázené únikem chladiva z primárního do sekundárního okruhu.
Piskáček Václav
core  

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

Effect of Thermal Period on Seed Dormancy of Damask Rose (Rosa damascena Mill.) [PDF]

open access: yesJournal of Medicinal Plants and By-products, 2012
Damask rose (Rosa damascena Mill.) has high economic importance and commercial value. The plant essential oil is used for perfumery, food and medicinal industries.
doaj  

Study of seed germination and dormancy of Prosopis farcta, Launaea acanthodes and Cressa cretica in pistachio orchards of Rafsanjan [PDF]

open access: yesعلوم و فناوری بذر ایران, 2017
In order to study the seed germination and dormancy of 3 weed species (Prosopis farcta, Launaea acanthodes and Cressa cretica) of pistachio orchards in Rafsanjan, Iran, three factorial experiments were conducted based on completely randomized design with
M. Khajeh-Hosseini   +3 more
doaj  

Germination rates and timing of Juglans californica at differing cold stratification temperatures

open access: yes, 2022
Juglans californica, the foundational species of walnut woodland communities in Southern California, is under threat from climate change. A temperature-dependent cold stratification period regulates seed germination of J.
Willette, Demian, Dr, Seid, Sabriya
core  

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

open access: yesAdvanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi   +7 more
wiley   +1 more source

Classification of Seed Dormancy in Pedicularis hallaisanensis Hurusawa: An Endemic and Endangered Species Native to Korea

open access: yesHorticulturae
Pedicularis hallaisanensis Hurusawa, native to Mt. Halla and Gaya, is an endangered endemic species. To support conservation efforts, this study investigated its germination characteristics and kind of seed dormancy. The seeds of P.
Hyeong-Bin Park   +7 more
doaj   +1 more source

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

open access: yesAdvanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma   +10 more
wiley   +1 more source

The Effect of Cold Stratification on the Germination of Grassland Seeds

open access: yes, 2022
One factor that must be considered when reconstructing a prairie is how the prairie seeds being planted need to be prepared for germination. The probability of successful germination of these seeds is dependent on many factors, including exposure to cold
Fynaardt, Gideon   +10 more
core  

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