Results 201 to 210 of about 182,891 (332)

Neonates with acute liver failure have higher overall mortality but similar posttransplant outcomes as older infants

open access: yesLiver Transplantation, EarlyView., 2022
Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala   +6 more
wiley   +1 more source

Bitter Taste Receptor Agonists Induce Apoptosis in Papillary Thyroid Cancer

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy, with a 20% recurrence rate. Bitter taste receptors (T2Rs) and their genes (TAS2Rs) may regulate survival in solid tumors. This study examined T2R expression and function in PTC cells.
Kimberly Wei   +6 more
wiley   +1 more source

The potential role of environmentally associated DNA methylation in childhood acute lymphoblastic leukaemia subtypes

open access: yesInternational Journal of Cancer, EarlyView.
What's New? The rarity of acute lymphoblastic leukaemia and lack of available environmental data have made the role of environmental factors in genetic subtypes challenging to investigate. Here, the authors performed a CpG‐level analysis to investigate DNA methylation as an intermediate mechanism between environmental risk exposures and acute ...
Jessica R. Saville   +5 more
wiley   +1 more source

Longitudinal monitoring of T cell dynamics in metastatic breast cancer via a remote diagnostic implant

open access: yesImmunoMedicine, EarlyView.
Abstract Metastatic triple negative breast cancer poses a significant health challenge due to rapid progression and limited treatment options. Immunotherapies targeting T cell responses against metastatic tumors depend on the presence of specific T cell phenotypes, which dynamically evolve with disease progression and treatment.
Ian A. Schrack   +10 more
wiley   +1 more source

Patient‐derived xenograft models in pan‐cancer: From bench to clinic

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract Patient‐derived xenograft (PDX) models provide a robust preclinical platform that preserves the genetic and phenotypic heterogeneity of patient tumors while mirroring their tumor genetic characteristics, which retain malignant cells and the tumor pathological structure, making them valuable for studying tumor progression and developing ...
Jiatong Li   +5 more
wiley   +1 more source

Physically crosslinked gelatin bio‐inks with enhanced printability, degradation and mechanical robustness for multi‐modal bioprinting

open access: yesInterdisciplinary Medicine, EarlyView.
A sustainable, physically crosslinked bio‐ink (Gel‐X) composed of gelatin, gellan gum, and Laponite XLG was developed for multi‐modal 3D bioprinting. Gel‐X is prepared within an hour by simple mixing in deionized water, eliminating the need for chemical crosslinkers.
Wei Long Ng   +4 more
wiley   +1 more source

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