Results 61 to 70 of about 3,873,674 (301)

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

The ecological genetics of senescence and stress resistance in Caenorhabditis elegans [PDF]

open access: yes, 2010
Longevity and the rate of senescence are determined by the ecological conditions during a population's recent evolutionary history, and are intrinsically linked to other components of life history and to fitness.
Savory, Fiona Rachel
core   +5 more sources

Functional Analysis of PbbZIP11 Transcription Factor in Response to Cold Stress in Arabidopsis and Pear

open access: yes, 2023
Cold stress is a prominent abiotic factor that adversely affects the growth and yield of pears, consequently restricting the cultivation range and resulting in substantial economic losses for the pear industry.
Yuxin Zhang   +7 more
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Attempt to express the Xerophyta viscose stress-responsive gene, Xvcor, in yeast with view to functional analysis [PDF]

open access: yes, 2002
Bibliography: leaves 24-29.Low temperature is one of the environmental factors that cause substantial crop losses in the world. Recent advances in the study of plants native from temperate regions, have established that cold acclimation is regulated at ...
Tawouokam, Jean Bernard
core   +1 more source

Cold stress reduces rice grain yield in temperate conditions

open access: yesRevista Brasileira de Engenharia Agrícola e Ambiental, 2022
This study aimed to evaluate the cold stress effect in natural field conditions by employing different rice sowing timings over three years, to identify national varieties tolerant to cold stress at the vegetative and generative stages, and to propose a ...
Rasim Unan   +2 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Proteome and phosphoproteome analysis of 2,4-epibrassinolide-mediated cold stress response in cucumber seedlings

open access: yesFrontiers in Plant Science, 2023
The 2, 4-epibrassinolide (EBR) significantly increased plants cold tolerance. However, mechanisms of EBR in regulating cold tolerance in phosphoproteome and proteome levels have not been reported. The mechanism of EBR regulating cold response in cucumber
Mengdi Zhou   +12 more
doaj   +1 more source

A transcriptomic approach to decipher cold stress mitigation exerted by the application of a brown-seaweed extract (BSE) in tomato.

open access: yes, 2023
reservedLo stress da freddo è uno dei principali stress abiotici che affliggono le piante coltivate, inducendo processi che causano una riduzione della produttività, e una limitazione dell’area geografica di coltivazione.
DAL FERRO, MARTINA
core  

Environmental stress responses in Lactococcus lactis [PDF]

open access: yes, 1999
Bacteria can encounter a variety of physical conditions during their life. Bacterial cells are able to survive these (often adverse) conditions by the induction of specific or general protection mechanisms. The lactic acid bacterium Lactococcus lactis is
Venema, Gerard,   +5 more
core   +2 more sources

Home - About - Disclaimer - Privacy