Results 81 to 90 of about 1,429,278 (309)

Repeatability of a cold stress test to assess cold sensitization [PDF]

open access: yesOccupational Medicine, 2015
Non-freezing cold injury (NFCI) is a syndrome in which damage to peripheral tissues occurs without the tissues freezing following exposure to low ambient temperatures.To assess the test-retest reliability of a cold stress test (CST) used to assess cold sensitization.Volunteers with no self-reported history of NFCI undertook the CST on three occasions ...
C M, House, R J, Taylor, E H N, Oakley
openaire   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Phenotypic variation in hypocotyl elongation among elite sand rice (Agriophyllum squarrosum) lines

open access: yesEcology and Evolution
Sand rice (Agriophyllum squarrosum), widely distributed in Central Arid Asia and prevalent in the sand dunes of northern China, presents a promising potential as a climate‐resilient crop.
Yujie Liu   +5 more
doaj   +1 more source

Evaluation of some defense enzymes activities in chickpea plants under cold stress [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2017
Plants require different defensive mechanisms for being survive and tolerance to environmental stresses. In present study, activity of defensive enzymes such as alternative oxidase (AOX), superoxide dismutase (SOD), catalase (CAT), electrolyte leakage ...
Samaneh Karami   +3 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

The Cold Peace: Russo-Western Relations as a Mimetic Cold War [PDF]

open access: yes, 2013
In 1989–1991 the geo-ideological contestation between two blocs was swept away, together with the ideology of civil war and its concomitant Cold War played out on the larger stage.
Asmus Ronald   +47 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Indices of adrenal cortical activity in men exposed to cold [PDF]

open access: yes, 1951
Thesis (M.A.)--Boston UniversityEvidence of physiological acclimatization of man to cold is scanty and not clear-cut. Certainly no adaptations have been described comparable to the dramatic changes which occur when men are acclimatized to heat.
Bass, David E.
core   +1 more source

The power spectra of CMB and density fluctuations seeded by local cosmic strings [PDF]

open access: yes, 1998
We compute the power spectra in the cosmic microwave background and cold dark matter (CDM) fluctuations seeded by strings, using the largest string simulations performed so far to evaluate the two-point functions of their stress energy tensor.
A. Albrecht   +26 more
core   +2 more sources

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