Results 51 to 60 of about 5,544,180 (301)

Transcription factors involved in cold response in plants. [PDF]

, 2010
Studies in Arabidopsis have shown cold stress tolerance can be enhanced by manipulation of the CBF/DREB and ICE transcription factor genes. To date, few studies have investigated CBF and ICE genes in crops species such as barley. Using a C-repeat element
Pillman, Katherine
core  

Effects of growth at cold hardening temperatures and temperature shifts on resistance to photoinhibition

, 1993
This chapter presents a summary of results that illustrate the photosynthetic responses of cold-tolerant cereals, spinach, and pine to low temperature-induced photoinhibition.
Boese, S.,, Huner, Ν.P.A.,, Malek, L.,, Hurry, V.M.,, Öquist, Gunnar,, Lapointe, L.,, Krol, M.,   +6 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Do Different Next-to-Skin Garments Change Thermal Sensation, Jump Height and Landing Knee Valgus After Cold Exposure?

Applied Sciences
Exposure to the cold can negatively affect muscle performance. This study compared the effects of two different full-length, lower body, next-to-skin garments on thermal sensation, countermovement jump (CMJ) height and knee frontal plane angle upon ...
Ben Kasehagen, Susan Morris, Kevin Netto
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Can we improve the identification of cold homes for targeted home energy-efficiency improvements? [PDF]

, 2006
Objective: To investigate the extent to which homes with low indoor-temperatures can be identified from dwelling and household characteristics.Design: Analysis of data from a national survey of dwellings, occupied by low-income households, scheduled for ...
Hong, SH, Warm Front Study Grp, Wilkinson, P, Hutchinson, EJ, Oreszczyn, T   +4 more
core  

Chill-coma and cold death temperature of Apis mellifera

, 1960
Worker bees have a lower chill‐coma temperature than drones or queens, which is influenced by their acclimatisation temperature as is their food consumption at a given temperature. Most bees die after 50 hrs.
Free, J. B., Spencer-Booth, Y., YVETTE SPENCER-BOOTH, J. B. FREE, Spencer-Booth, Yvette   +4 more
core   +1 more source

Neurosensory and vascular function after 14 months of military training comprising cold winter conditions

Scandinavian Journal of Work, Environment & Health, 2016
OBJECTIVE: This study aimed to examine the effects of 14 months of military training comprising cold winter conditions on neurosensory and vascular function in the hands and feet.
Daniel Carlsson, Hans Pettersson, Lage Burström, Tohr Nilsson, Jens Wahlström   +4 more
doaj   +1 more source

Metabolism Reorganization in Kale (Brassica oleracea L. var acephala) Populations with Divergent Glucosinolate Content under Thermal Stresses

Agronomy, 2022
Thermal stress causes the reduction in productivity and harvest quality. To adapt to different temperature ranges, plants activate protecting metabolic pathways.
María Díaz-Urbano, Pablo Velasco, María Elena Cartea, Víctor M. Rodríguez   +3 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source