Results 81 to 90 of about 8,965,053 (394)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Kolmogorov cosmic microwave background sky

, 2009
A new map of the sky representing the degree of randomness in the cosmic microwave background (CMB) temperature has been obtained. The map based on estimation of the Kolmogorov stochasticity parameter clearly distinguishes the contribution of the ...
A. A. Kocharyan, A. E. Allahverdyan, A. L. Kashin, Arnold, Copi, E. Poghosian, Eriksen, G. Yegorian, Gurzadyan, Gurzadyan, Gurzadyan, Gurzadyan, Gurzadyan, Gurzadyan, Górski, H. G. Khachatryan, H. Kuloghlian, Inoue, Kolmogorov, Kovac, Rudnick, S. Mirzoyan, Smoot, T. Ghahramanyan, V. G. Gurzadyan, Vielva, Wiltshire   +26 more
core   +1 more source

Benzonitrile as a Proxy for Benzene in the Cold ISM: Low-temperature Rate Coefficients for CN + C₆H₆ [PDF]

, 2020
The low-temperature reaction between CN and benzene (C₆H₆) is of significant interest in the astrochemical community due to the recent detection of benzonitrile, the first aromatic molecule identified in the interstellar medium (ISM) using radio ...
Cooke, Ilsa R., Gupta, Divita, Messinger, Joseph P., Sims, Ian R.   +3 more
core  

The impact of heat waves and cold spells on mortality rates in the Dutch population. [PDF]

, 2001
We conducted the study described in this paper to investigate the impact of ambient temperature on mortality in the Netherlands during 1979-1997, the impact of heat waves and cold spells on mortality in particular, and the possibility of any heat wave ...
Huynen, M M, Kunst, A E, Martens, P, Schram, D, Weijenberg, M P   +4 more
core   +2 more sources

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Perubahan karakteristik fisikokimia dan mikrobiologi ketupat selama penyimpanan suhu dingin [Changes on physicochemical and microbiological characteristics of ketupat during storage at cold temperature]

Jurnal Teknologi & Industri Hasil Pertanian, 2022
Ketupat is an Indonesian indigenous food made from rice which is wrapped by young coconut leaves and cooked into the boiling water. Storage temperatures might affect the physicochemical and microbiological characteristics of ketupat.
Isnaini Rahmadi, Sugiyono Sugiyono, Nugraha Edhi Suyatma   +2 more
doaj   +1 more source

Nonlinear interaction between three inertial Alfv\'{e}n waves [PDF]

, 2006
The resonant coupling between Alfv\'{e}n waves is reconsidered. New results are found for cold plasmas there temperature effects are negligible.Comment: To appear in J.
Brodin, G., Shukla, P. K., Stenflo, L.
core   +2 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Cold Temperature Adaptation and Growth of Microorganisms

Journal of Food Protection, 1997
Most microorganisms must accommodate a variety of changing conditions and stresses in their environment in order to survive and multiply. Because of the impact of temperature on all reactions of the cell, adaptations to fluctuations in temperature are possibly the most common. Widespread in the environment and well-equipped for cold temperature growth,
Elaine D. Berry, P.M. Foegeding
openaire   +3 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source