Results 41 to 50 of about 2,497,077 (294)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Swiftly following World War Two, the Cold War between a Soviet-led alliance and an American-led one might appear to be a clearcut case of a continuity with Mackinder’s 1904 perspective.
Jeremy BLACK
doaj +1 more source
The collapse of the Soviet Union, which resulted in the demise of the fonner bipolar system in international relations, has led writers to offer predictions about the future framework of international political relationships.
Mohamed Karbal
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The recognition of Slovenia and Croatia was a defining moment in the history of the post-Cold War order in Europe. From the outset, this step was a controversial one, and scholars focussing on the role of the United Kingdom often claim that London’s ...
Methfessel Christian
doaj +1 more source
Reconceptualising localised Cold Wars in southern Africa
This article aims to examine how localised conditions contributed to the shaping and maintenance of the Cold War in southern Africa during the last three decades of the Cold War.
Mitchell Yates, Drew Cottle
doaj +1 more source
Från ett kallt krig till ett annat
: From One Cold War to Another Klaus Carsten Pedersen (Det Udenrigspolitiske Selskab,) reviews Från ett kallt krig till ett annat (From One Cold War to Another) written by Thomas Bertelman.
Klaus Carsten Pedersen
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Indonesia, the Cold War and Non-alignment: Relations of the Early Indonesian Cabinets with the United States, 1950-1952. The Cold War initially focused on Europe but promptly spread to encompass the entire globe.
Richard Mason
doaj

