Results 51 to 60 of about 3,064,809 (249)

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Bunkers Revisited : Co-producing Memory, Meaning and Materiality in Danish Cold War Museums

The Cold War shaped the Danish landscape and cityscape profoundly. Numerous bunkers, military and civilian remain today as testimonies of a time where fear of a nuclear Third World War was imminent.
Farbøl, Rosanna
core   +2 more sources

The terms “Cold War” and “Second Cold War” in the light of contemporary socio-humanities: an encyclopedic perspective [PDF]

Енциклопедичний Вісник України
This article explores the evolving meanings of the terms "Cold War" and "Second/New Cold War" within contemporary socio-humanities.
Oleksii Yas
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Cold War History beyond the Cold War Discourse: A Conversation with Łukasz Stanek

Architectural Histories, 2019
This interview engages with Łukasz Stanek in a conversation that contextualizes the Special Collection in Architectural Histories on Marxism and architectural theory across the East-West divide.
Hilde Heynen, Sebastiaan Loosen
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Features of the "Monumental" Policy of the United States in Relation to the Conflicts of the Cold War (on the Example of Monuments in Washington, D.C.)

Известия Алтайского государственного университета, 2023
In this article, the authors analyze the unique features of the United States' "monumental" policy in relation to the conflicts of the Cold War and the associated memorial and commemorative spaces within the metropolitan region. Specifically, the authors
Влада Евгеньевна Дергачева, Юрий Георгиевич Чернышов   +1 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Cold War in Southern Africa Kalter Krieg im Südlichen Afrika

Africa Spectrum, 2010
Review Article: Cold War in Southern Africa Gary Baines, Peter Vale (eds.) (2008), Beyond the Border War: New Perspectives on Southern Africa’s Late-Cold War Conflicts, Pretoria: Unisa Press, ISBN 978 1 86888 456 8, xix + 342 pp. Sue Onslow (ed.) (2009),
Matthew Graham
doaj  

HAS THE PERIOD OF 'CIVILIAN POWER EUROPE' COME TO AN END?

Ankara Avrupa Çalışmaları Dergisi, 2002
During the Cold War, to the extent that it performed at the international stage, the European Community was portrayed as a ‘civilian power’, because it lacked the relevant military instruments and relied on ‘economic and diplomatic means’ to try to ...
Sinem Akgül Açıkmeşe
doaj   +1 more source