Results 51 to 60 of about 2,497,077 (294)

Cold War as Social Conflict, Iron Curtains and Application of Dѐtente Policy as Cold War Concept

open access: yesInternational Studies Journal, 2022
This paper is to evaluate the peculiarity of iron curtain that was to fortified borders in central Europe, because it was not used to describe similar border between communist and capitalist states basis.
Effiong Ekpo, Udeoji Ebele Angela
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Tearing down the ‘buckskin curtain’: domestic policy-making and Indigenous intellectuals in the Cold War United States and Canada [PDF]

open access: yes, 2022
North American Indigenous peoples remain overlooked in Cold War scholarship, despite being tangibly impacted by this global conflict. This article presents a study of four foundational texts, to argue that the Cold War shaped the introduction of new ...
Humalajoki Reetta
core   +1 more source

GERMAN DEMOCRATIC REPUBLIC ESPIONAGE IN SCHLESWIG-HOLSTEIN [PDF]

open access: yesRomanian Intelligence Studies Review
The network of intelligence positions of the HV A in Schleswig- Holstein did not emerge overnight, but was rather the product of a long development process.
Helmut MÜLLER-ENBERGS
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

The terms “Cold War” and “Second Cold War” in the light of contemporary socio-humanities: an encyclopedic perspective [PDF]

open access: yesЕнциклопедичний Вісник України
This article explores the evolving meanings of the terms "Cold War" and "Second/New Cold War" within contemporary socio-humanities.
Oleksii Yas
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

"Russia Accuses Fleet Street": Journalists and MI6 during the Cold War [PDF]

open access: yes, 2015
An interesting but under-researched area of journalism studies is the relationship between journalists, particularly foreign correspondents, and the intelligence services during the cold war.
Dorril, Stephen
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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