Results 61 to 70 of about 43,879 (263)
Cold War historiography at the crossroads [PDF]
How is the Cold War understood in an expanding and diversifying historiographical field? Conceptual precision and specificity seem to be giving way to a looser understanding of the Cold War as an era that encompassed different although interconnected conflicts and transformations.
openaire +3 more sources
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
The interview with Richars Sakwa has been held in dramatic days when the New Cold war became an evident reality and the British-Russian crisis provoked the fall of diplomacy between Russia and vast majority of the western countries.
Richard Sakwa +1 more
doaj +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Odd Arne Westad is a historian whose work largely focuses on the Cold War as well as on Chinese and East Asian history. He is best known as a key voice of ‘new Cold War history’, an expanding field which, since the turn of the century, has sought ...
Rui Lopes
doaj +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Reconsidering Development Aid: A Systemic Analysis
In the political and academic debates on development aid in the post-Cold War years, there is often reference to a “new aid architecture.” This study explores what is new about this “new architecture of aid” and traces change and continuity by comparing ...
Yahya Gülseven
doaj +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Die Koue Oorlog: Die Wêreld se Langste Oorlog? / The Cold War: The World's Longest War?
The Cold War is a war that was never declared and never terminated. Historians differ rather seriously on when, how and where it began. They do not, however, differ on the fact that it simply faded away at the end of the eighties, but they assign ...
P.H. Kapp
doaj +1 more source

