Results 131 to 140 of about 69,892 (209)

To Raise or Not to Raise: An Experimental Test of Community Support for Increasing the Minimum Age of Criminal Responsibility in New South Wales, Australia

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT While research has identified a disconnect between the minimum age of criminal responsibility (MACR) and public perceptions of criminal culpability among young people, no study has examined how offender characteristics influence support for reform using an experimental design. To address this, this study presents the first experimental test of
Cameron T. Langfield   +3 more
wiley   +1 more source

Dosing Interval Extension of Dupilumab in CRSwNP: Five‐Year Real World Outcomes

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent, often Type 2‐mediated inflammatory disease that markedly impairs quality of life. While dupilumab provides rapid improvement, there is limited evidence on long‐term outcomes beyond 2 years, and the clinical impact of dosing‐interval extension remains unclear.
Nicholas J. Campion   +15 more
wiley   +1 more source

Accounting for missing data in public health research using a synthesis of statistical and mathematical models. [PDF]

open access: yesJ Epidemiol Community Health
Zivich PN   +4 more
europepmc   +1 more source

Neurofilament Proteoforms in Amyotrophic Lateral Sclerosis Are Different in Cerebrospinal Fluid and Blood

open access: yesAnnals of Neurology, EarlyView.
We used targeted immunopurification‐mass spectrometry (IP‐MS) to characterize human neurofilament light chain (NfL) proteoforms across various compartments to assess their alterations in amyotrophic lateral sclerosis (ALS). NfL is truncated in cerebrospinal fluid (CSF) and blood in patients with sporadic ALS (sALS) and these proteoforms differ between ...
John B. Coulton   +11 more
wiley   +1 more source

When Does Alzheimer's Disease Start? Plasma Aβ42/40 Assays Show Steep Changes at Aβ‐PET Centiloid 15, Mean Age of 66 Years

open access: yesAnnals of Neurology, EarlyView.
Objective Sporadic late‐onset Alzheimer's disease (AD) is characterized by a long pre‐clinical phase where amyloid‐beta (Aβ) and tau begin to accumulate in the brain. The primary objective was to determine the age at which AD starts by finding the average population age when both positron emission tomography (PET) Aβ (Aβ‐PET) and plasma Aβ42/40 become ...
Rodrigo Cánovas   +29 more
wiley   +1 more source

Tailoring Electronic Properties of Precision Graphene Nanoribbons via Nanopore Engineering

open access: yesAngewandte Chemie, EarlyView.
Novel porous graphene nanoribbons incorporating [18]annulene nanopores, together with a nonporous GNR of identical width, have been synthesized. Spectroscopic and theoretical analyses reveal that nanopore incorporation effectively tunes their electronic properties by enlarging the bandgap, reducing charge‐carrier mobility, and modulating exciton ...
Kun Liu   +19 more
wiley   +2 more sources

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