Results 31 to 40 of about 69,892 (209)
In this study, the dielectric constant, dielectric loss, conductivity and capacitance of the electronic electroactive polymer (EEAP) were systematically tested experimentally, and the effects of different frequencies, effective voltages, electrode types,
Hong Wang, Liang Yang
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Parameter Identification for a New Circuit Model Aimed to Predict Body Water Volume
Intracellular and extracellular water volumes in the human body have been computed using a sequence of models starting with a linear first order RC circuit (Cole model) and finishing with the De Lorenzo model. This last model employs a fractional order
GHEORGHE, A.-G. +3 more
doaj +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Modeling of linear dispersive materials using scalable time domain finite element scheme
This paper deals with some aspects of formulation and implementation of a broadband algorithm with build-in analysis of some dispersive media. The construction of the finite element method (FEM) based on direct integration of Maxwell’s equations and ...
Butryło Bogusław
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Feasibility of Sectional Bioelectrical Impedance Spectrum Evaluating Joint Effusion in Rat
Background: Joint effusion is a significant cause of disability worldwide. Practical assessment and diagnosis can avoid the secondary damage caused by the effusion. Nowadays, bioimpedance spectroscopy (BIS) is an emerging tool to differentiate biological
Jia Chen, Li Ke, Qiang Du, Zhe Long
doaj +1 more source
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Microwave Spectroscopy Investigation of Carasau Bread Doughs: Effects of Composition up to 8.5 GHz
Carasau bread is a flat bread, typical of Sardinia (Italy). The market of this food product has a large growth potential, and its industry is experiencing a revolution, characterized by digitalization and automation.
Claudia Macciò +8 more
doaj +1 more source
Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron +5 more
wiley +1 more source

