Results 51 to 60 of about 1,278 (162)

Distinct Roles of IL‐4, IL‐13, and IL‐22 in Human Skin Barrier Dysfunction and Atopic Dermatitis

Allergy, Volume 81, Issue 2, Page 480-497, February 2026.
This study reports the distinct effects of IL‐4, IL‐13, and IL‐22 on bio‐stabilized human skin with intact barriers and immune cells. IL‐4, IL‐13, and IL‐22 upregulate inflammatory mediators, disrupt skin barrier integrity, and reciprocally modulate IL‐4Rα and IL‐22Rα1 receptors.
Paolo D'Avino, Juno Kim, Manru Li, Philipp Gessner, Patrick Westermann, Yagız Pat, Carina Beha, Claudia Traidl‐Hoffmann, Jeremy Bost, Nicolas Gaudenzio, Christoph B. Messner, Cezmi A. Akdis, Yasutaka Mitamura   +12 more
wiley   +1 more source

Hipoparatireoidismo primário manifestando-se com aumento de enzimas musculares Primary hypoparathyreoidism with raised muscle enzymes

Revista Brasileira de Reumatologia, 2005
Os autores relatam o caso de um jovem de 18 anos de idade com fraqueza muscular generalizada, cãibras e crises convulsivas, tratado com corticosteróides por oito anos em decorrência de um diagnóstico de polimiosite, sem melhora clínica.
Simone Appenzeller, Gláucio W. R. Castro, Sandra Regina Fernandes, Adil M. Samara, Manoel B. Bértolo   +4 more
doaj   +1 more source

Clinical Implementation of Pharmacogenomics and Drug–Drug Interaction Screening in a German Academic Teaching Hospital and Outpatient Follow‐Up

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 241-254, January 2026.
Overview of the implemented pharmacogenomics (PGx) process in clinical routine at the Robert Bosch Hospital: from patient enrollment via the hospital information system, DNA detection using a customized TaqMan OpenArray panel and qPCR for CNV assessment, to clinical translation of genotyping results into PGx guideline‐based recommendations using a ...
Roman Tremmel, Filippa Schreeck, Simon Jaeger, Severin Schricker, Elke Schaeffeler, Svitlana Igel, Daniela Steinberger, Manuel Pagitz, Jörg Latus, Markus Ketteler, Kerstin Bühl, Marc‐H. Dahlke, Hans‐Georg Kopp, Matthias Schwab   +13 more
wiley   +1 more source

Vitamina D y salud ósea

Perspectivas en Nutrición Humana, 2005
La vitamina D tiene un papel esencial en la homeostasis del calcio y de la salud ósea, sin embargo, investigaciones recientes han revelado que su forma activa, la 1,25-Dihidroxivitamina D (1,25 (OH2) D3 (D2)) tiene otras acciones biológicas en las ...
Gustavo Lozano Casabianca, María Elena Maldonado Celis, Diego Alejandro Gaitán Charry   +2 more
doaj  

Medication‐Related Osteonecrosis of the Jaws in Patients on Antiresorptive Medication With Dental Implants. A Scoping Review

Clinical Oral Implants Research, Volume 36, Issue 10, Page 1173-1201, October 2025.
ABSTRACT Objectives Patients receiving antiresorptive medication (AR) for osteoporosis or cancer are at risk of medication‐related osteonecrosis of the jaws (MRONJ), especially after surgical procedures. Dental implant (DI) placement in high‐dose AR (HDAR) patients is widely discouraged, and thorough counseling is recommended for low‐dose AR (LDAR ...
Sanne Werner Moeller Andersen, Nishma Vandvig Hindocha, Iben Poulsen, Henning Schliephake, Simon Storgård Jensen   +4 more
wiley   +1 more source

Bone health in a U.K. cohort of youth living with perinatally acquired HIV‐1: a longitudinal study

Journal of the International AIDS Society, Volume 28, Issue 9, September 2025.
Abstract Introduction Low bone mineral density (BMD) has been described in children and young people with perinatally acquired HIV (PHIV), which may be related to both traditional (e.g. low body mass index and malnutrition) and HIV‐related risk factors (e.g. longstanding exposure to HIV and antiretroviral therapy [ART], with immune suppression, chronic
Merle Henderson, Alexandra Blenkinsop, Oliver Ratmann, Moira Cheung, Hermione Lyall, Sarah Fidler, Caroline Foster, the BONDY study group   +7 more
wiley   +1 more source

Vitamin D deficiency and clinical correlations in systemic sclerosis patients: A retrospective analysis for possible future developments.

PLoS ONE, 2017
ObjectiveAssessment of serum 25-hydroxyvitamin D (25(OH)D) correlations with clinical parameters and evaluation of the efficacy of standard oral supplementation in systemic sclerosis (SSc) patients.Methods154 SSc patients were recruited, in all seasons ...
Amelia Chiara Trombetta, Vanessa Smith, Emanuele Gotelli, Massimo Ghio, Sabrina Paolino, Carmen Pizzorni, Amber Vanhaecke, Barbara Ruaro, Alberto Sulli, Maurizio Cutolo   +9 more
doaj   +1 more source

Análise dos valores da vitamina D em diferentes grupos populacionais

RevSALUS
Introdução: A vitamina D é uma hormona que atua diretamente na saúde óssea, no crescimento celular saudável, na imunidade, na musculatura, no metabolismo e noutros sistemas, como o sistema cardiovascular e o sistema nervoso.
Sílvia Mota, Maria Lopes, Maria Lamas, Maria Sousa   +3 more
doaj   +1 more source

VITAMINA D Y ASMA

Neumología Pediátrica, 2019
La principal fuente de Vitamina D es la bioconversión del 7-dehidrocolesterol a colecalciferol, sin embargo, el nivel de exposición solar se ha reducido drásticamente durante las últimas décadas, por lo que no es extraño encontrar un déficit elevado de ...
Selim Abara
doaj   +1 more source

Avaliação do efeito tipo antidepressivo da associação de colecalciferol e da curcumina em um modelo animal de depressão induzido por lipopolissacarídeo

, 2022
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Bioquímica, Florianópolis, 2022.O Transtorno Depressivo Maior (TDM) é um transtorno psiquiátrico muito prevalente em todo o mundo
Torrá, Ana Clara Nass da Cruz
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