Results 41 to 50 of about 763 (143)

Plasma inflammatory biomarker profiles across the Alzheimer's disease spectrum in the Bio‐Hermes cohort

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Inflammation contributes to Alzheimer's disease (AD), but its stage‐specific and amyloid‐dependent patterns remain unclear. METHODS We analyzed 964 participants from the Bio‐Hermes cohort (cognitively normal [CN] = 404, mild cognitive impairment [MCI] = 302, mild AD = 258). Plasma levels of 32 cytokines, neurofilament light chain (
Zain Hussain, Dominic Ng, Samuel Leighton, Fani Deligianni, Craig Ritchie, Jonathan Cavanagh   +5 more
wiley   +1 more source

Acquired Multiple Acyl‐Coenzyme A Dehydrogenase Deficiency Associated With Sertraline in Sweden—A Nationwide Population‐Based Study

European Journal of Neurology, Volume 33, Issue 3, March 2026.
Multiple acyl‐coenzyme A dehydrogenase deficiency‐like disease has recently been described as a rare adverse effect of sertraline. We performed a nationwide population‐based retrospective study in Sweden (2014–2024) including 40 patients, corresponding to an incidence of 1.24 per 100,000 treated individuals per year.
Sofie Sunebo, Emil Nilsson, Martin Engvall, Carola Hedberg‐Oldfors, Yan Shen, Inger Nennesmo, Olof Danielsson, Anders Oldfors, Hanna Appelqvist, Ulrika Lindgren   +9 more
wiley   +1 more source

Native vitamin D in pre-dialysis chronic kidney disease

Nefrología, 2019
Chronic kidney disease patients have a high prevalence of vitamin D insufficiency/deficiency. Vitamin D deficiency has been associated with a variety of bone, metabolic and cardiovascular disorders.
Mariana P. Cardoso, Luciano A.L. Pereira
doaj   +3 more sources

Distinct Roles of IL‐4, IL‐13, and IL‐22 in Human Skin Barrier Dysfunction and Atopic Dermatitis

Allergy, Volume 81, Issue 2, Page 480-497, February 2026.
This study reports the distinct effects of IL‐4, IL‐13, and IL‐22 on bio‐stabilized human skin with intact barriers and immune cells. IL‐4, IL‐13, and IL‐22 upregulate inflammatory mediators, disrupt skin barrier integrity, and reciprocally modulate IL‐4Rα and IL‐22Rα1 receptors.
Paolo D'Avino, Juno Kim, Manru Li, Philipp Gessner, Patrick Westermann, Yagız Pat, Carina Beha, Claudia Traidl‐Hoffmann, Jeremy Bost, Nicolas Gaudenzio, Christoph B. Messner, Cezmi A. Akdis, Yasutaka Mitamura   +12 more
wiley   +1 more source

Clinical Implementation of Pharmacogenomics and Drug–Drug Interaction Screening in a German Academic Teaching Hospital and Outpatient Follow‐Up

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 241-254, January 2026.
Overview of the implemented pharmacogenomics (PGx) process in clinical routine at the Robert Bosch Hospital: from patient enrollment via the hospital information system, DNA detection using a customized TaqMan OpenArray panel and qPCR for CNV assessment, to clinical translation of genotyping results into PGx guideline‐based recommendations using a ...
Roman Tremmel, Filippa Schreeck, Simon Jaeger, Severin Schricker, Elke Schaeffeler, Svitlana Igel, Daniela Steinberger, Manuel Pagitz, Jörg Latus, Markus Ketteler, Kerstin Bühl, Marc‐H. Dahlke, Hans‐Georg Kopp, Matthias Schwab   +13 more
wiley   +1 more source

Hipoparatireoidismo primário manifestando-se com aumento de enzimas musculares Primary hypoparathyreoidism with raised muscle enzymes

Revista Brasileira de Reumatologia, 2005
Os autores relatam o caso de um jovem de 18 anos de idade com fraqueza muscular generalizada, cãibras e crises convulsivas, tratado com corticosteróides por oito anos em decorrência de um diagnóstico de polimiosite, sem melhora clínica.
Simone Appenzeller, Gláucio W. R. Castro, Sandra Regina Fernandes, Adil M. Samara, Manoel B. Bértolo   +4 more
doaj   +1 more source

Medication‐Related Osteonecrosis of the Jaws in Patients on Antiresorptive Medication With Dental Implants. A Scoping Review

Clinical Oral Implants Research, Volume 36, Issue 10, Page 1173-1201, October 2025.
ABSTRACT Objectives Patients receiving antiresorptive medication (AR) for osteoporosis or cancer are at risk of medication‐related osteonecrosis of the jaws (MRONJ), especially after surgical procedures. Dental implant (DI) placement in high‐dose AR (HDAR) patients is widely discouraged, and thorough counseling is recommended for low‐dose AR (LDAR ...
Sanne Werner Moeller Andersen, Nishma Vandvig Hindocha, Iben Poulsen, Henning Schliephake, Simon Storgård Jensen   +4 more
wiley   +1 more source

Vitamina D y salud ósea

Perspectivas en Nutrición Humana, 2005
La vitamina D tiene un papel esencial en la homeostasis del calcio y de la salud ósea, sin embargo, investigaciones recientes han revelado que su forma activa, la 1,25-Dihidroxivitamina D (1,25 (OH2) D3 (D2)) tiene otras acciones biológicas en las ...
Gustavo Lozano Casabianca, María Elena Maldonado Celis, Diego Alejandro Gaitán Charry   +2 more
doaj  

Bone health in a U.K. cohort of youth living with perinatally acquired HIV‐1: a longitudinal study

Journal of the International AIDS Society, Volume 28, Issue 9, September 2025.
Abstract Introduction Low bone mineral density (BMD) has been described in children and young people with perinatally acquired HIV (PHIV), which may be related to both traditional (e.g. low body mass index and malnutrition) and HIV‐related risk factors (e.g. longstanding exposure to HIV and antiretroviral therapy [ART], with immune suppression, chronic
Merle Henderson, Alexandra Blenkinsop, Oliver Ratmann, Moira Cheung, Hermione Lyall, Sarah Fidler, Caroline Foster, the BONDY study group   +7 more
wiley   +1 more source

Vitamin D deficiency and clinical correlations in systemic sclerosis patients: A retrospective analysis for possible future developments.

PLoS ONE, 2017
ObjectiveAssessment of serum 25-hydroxyvitamin D (25(OH)D) correlations with clinical parameters and evaluation of the efficacy of standard oral supplementation in systemic sclerosis (SSc) patients.Methods154 SSc patients were recruited, in all seasons ...
Amelia Chiara Trombetta, Vanessa Smith, Emanuele Gotelli, Massimo Ghio, Sabrina Paolino, Carmen Pizzorni, Amber Vanhaecke, Barbara Ruaro, Alberto Sulli, Maurizio Cutolo   +9 more
doaj   +1 more source