Results 91 to 100 of about 38,268 (268)

Bowel Urgency Improvement Correlates With Clinical, Biochemical, and Intestinal Ultrasound Improvements in Inflammatory Bowel Disease: A Cross Sectional Multicenter Study

United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background Bowel urgency (BU) is reported by over 80% of patients with ulcerative colitis (UC) and 60% of those with Crohn's disease (CD). However, the impact of advanced therapies on BU has not been consistently evaluated. Objectives To assess the effect of advanced therapies on BU improvement in patients with UC and CD.
Ferdinando D'Amico, Olga Maria Nardone, Alessandro Bruno, Mariangela Allocca, Alessandra Zilli, Federica Furfaro, Tommaso Lorenzo Parigi, Virginia Solitano, Federica Ungaro, Ilaria Faggiani, Alessia La Mantia, Giulio Calabrese, Gionata Fiorino, Vipul Jairath, Laurent Peyrin‐Biroulet, Luca Massimino, Fabiana Castiglione, Silvio Danese   +17 more
wiley   +1 more source

Filgotinib Is an Effective and Safe Treatment Option for Difficult‐To‐Treat Ulcerative Colitis: Real‐World Evidence of the Dutch Initiative on Crohn and Colitis (ICC) Registry

United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background Filgotinib is a preferential Janus kinase 1 (JAK‐1) inhibitor registered for the treatment of ulcerative colitis (UC). Real‐world effectiveness of filgotinib, especially for difficult‐to‐treat (DTT, failure of ≥ 2 prior advanced therapies) patients, has been scarcely reported.
M. R. Naber, A.E van der Meulen, P. W. Voorneveld, S. H. C. Veltkamp, A.A. van Bodegraven, A. Bodelier, Z. Mujagic, M. Pierik, L. M. M. Verleye, M. Duijvestein, D. G. Bouwknegt, M. C. Visschedijk, N. Srivastava, R. L. West, B. Oldenburg, M. Löwenberg, F.D.M. van Schaik, On behalf of the Dutch ICC Registry   +17 more
wiley   +1 more source

Autologous Adipose Tissue Injection as Treatment for Ileoanal Pouch‐Related Fistulae

United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background Ileal pouch‐anal anastomosis (IPAA) is a standard surgical procedure for ulcerative colitis (UC) and familial adenomatous polyposis. However, pouch‐related fistulae (PRF) are a significant complication. There is no consensus on the optimal treatment for PRF.
Hayder Alqaisi, Anders Dige, Ole Thorlacius‐Ussing, Lilli Lundby   +3 more
wiley   +1 more source

Immune‐Mediated Thrombocytopenia in an Ulcerative Colitis Patient After Initiating Filgotinib Treatment: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
Timeline of events ABSTRACT Moderate‐to‐severe ulcerative colitis can be effectively treated with JAK‐1 inhibition, but platelet counts should be closely monitored, especially in active disease. We confirmed immune‐mediated thrombocytopenia (ITP) in one of our patients after the initiation of filgotinib. Whether this was drug‐induced is uncertain.
M. J. van der Hoff, F. El‐Morabit, M. Löwenberg   +2 more
wiley   +1 more source

Impact of Hospital Volume on Postoperative Morbidity and Mortality Following a Colectomy for Ulcerative Colitis [PDF]

, 2008
Gilaad G. Kaplan, Ellen P. McCarthy, John Z. Ayanian, Joshua R. Korzenik, Richard A. Hodin, Bruce E. Sands   +5 more
openalex   +1 more source

Management of the Rectal Stump after Subtotal Colectomy Operations for Inflammatory Bowel Disease in the Era of Immunologic Therapy: A Two-Centre Cohort Study

, 2023
Dominika Boldovjáková, Islam El-Abbassy, Inari Alarcon, Mamoun El-Saify, Juen Hao Chan, Morag Harley, Craig Parnaby, Angus Watson, George Ramsay   +8 more
openalex   +1 more source

Medulla Tetrapanacis Water Extract Ameliorates Dextran Sulfate Sodium‐Induced Ulcerative Colitis by Reprogramming Macrophage Polarization and Maintaining Intestinal Barrier Integrity

Food Frontiers, Volume 7, Issue 1, January 2026.
The protective effects of Medulla Tetrapanacis (MT) water extract on dextran sulfate sodium‐induced ulcerative colitis (UC) were examined both in vivo (mouse and zebrafish) and in vitro. The effect of MT on UC was mediated by regulating macrophage polarization, ameliorating oxidative stress, and preserving an intact intestinal barrier. The effect of MT
Yanfen Cheng, Carsten Tsun‐Ka Kwok, Zi‐Wen Yang, Xi Feng, George Pak‐Heng Leung, Simon Ming‐Yuen Lee, Franklin Wang‐Ngai Chow, Lele Zhang, Daniel Kam‐Wah Mok, Sai‐Wang Seto, Jingjing Li   +10 more
wiley   +1 more source

Long-term results of medical treatment in patients with a severe attack of ulcerative colitis

Терапевтический архив, 2015
Aim. To assess the long-term result of medical treatment in patients with a severe attack (SA) of ulcerative colitis (UC). Subjects and methods. The course of UC was analyzed in 56 patients who were accessible by telephone contact and consecutively ...
I L Khalif, B A Nanaeva, A O Golovenko, O V Golovenko   +3 more
doaj  

Duodenitis associated with ulcerative colitis and pouchitis after total colectomy successfully treated with upadacitinib: A case report

DEN Open
A 27‐year‐old man had ulcerative colitis (UC) 1 year prior and underwent a colectomy and two‐stage ileal pouch‐anal anastomosis for medically refractory UC 6 months ago.
Kentaro Kojima, Jun Takada, Kiichi Otani, Naoya Masuda, Yukari Tezuka, Sachiyo Onishi, Masaya Kubota, Takashi Ibuka, Masahito Shimizu   +8 more
doaj   +1 more source

P523 Cyclosporin rescue therapy is as effective as infliximab at preventing colectomy [PDF]

, 2014
S. O'Connor, M. Lalji, Gerald Holtmann, P. Pillans, Neal Martin, Daniel Burger   +5 more
openalex   +1 more source