Results 121 to 130 of about 83,305 (348)
(1) Background: Familial adenomatous polyposis (FAP) is a hereditary condition characterized by the development of numerous adenomas in the large intestine, often necessitating colectomy due to an elevated risk of colorectal cancer.
Jarosław Cwaliński +6 more
doaj +1 more source
ABSTRACT Background Filgotinib is a preferential Janus kinase 1 (JAK‐1) inhibitor registered for the treatment of ulcerative colitis (UC). Real‐world effectiveness of filgotinib, especially for difficult‐to‐treat (DTT, failure of ≥ 2 prior advanced therapies) patients, has been scarcely reported.
M. R. Naber +17 more
wiley +1 more source
In a large‐scale, multiple‐site Danish faecal microbiota transplantation (FMT) system, the cure rates in patients with Clostridioides difficile infection treated with encapsulated FMT were improved following exclusion of three low‐performing donors and implementation of a two‐dose FMT regimen.
Sara Ellegaard Paaske +17 more
wiley +1 more source
Perineal rectosigmoidectomy on treatment of rectal procidentia: analysis of 48 cases
OBJECTIVE: To evaluate results obtained in 48 cases of perineal rectosigmoidectomy in patients with rectal procidentia. METHODS: 48 medical records of patients undergoing PRS were analyzed, retrospectively.
Bruno Amaral Medeiros +7 more
doaj
High Risk of Colorectal Cancer After High‐Grade Dysplasia in Inflammatory Bowel Disease Patients
The advantages of colon‐sparing treatment for high‐grade dysplasia should be weighed against the higher risk of metachronous colorectal cancer and the subsequent need for stringent endoscopic surveillance. ABSTRACT Background There are limited data on colorectal cancer (CRC) risk after high‐grade dysplasia in inflammatory bowel disease.
Monica E. W. Derks +4 more
wiley +1 more source
BRIP-1 germline mutation and its role in colon cancer: presentation of two case reports and review of literature. [PDF]
BackgroundHereditary colon cancer is characterized by the inheritance of an abnormal gene mutation which predisposes to malignancy. Recent advances in genomic medicine have identified mutations in "novel" genes as conferring an increased risk of ...
Ali, Mir +2 more
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Impact of thiopurines and anti-tumour necrosis factor therapy on hospitalisation and long-term surgical outcomes in ulcerative colitis. [PDF]
Ulcerative colitis (UC) is a chronic inflammatory condition affecting the large bowel and is associated with a significant risk of both requirement for surgery and the need for hospitalisation. Thiopurines, and more recently, anti-tumour necrosis factor (
Alexakis, C, Pollok, RC
core +1 more source
This illustration summarises our primary findings highlighting the rising incidence of certain extra‐digestive cancers among persons with IBD over the 25‐year study duration (left), and the relative rates of extra‐digestive cancer incidence and mortality among persons with IBD in recent years (2010–2019) compared to their age‐ and sex‐matched controls (
Sanjay K. Murthy +13 more
wiley +1 more source
Prevalence and risk factors of gallstone disease in Korean patients with ulcerative colitis [PDF]
Background/Aims The prevalence of gallstone disease in patients with ulcerative colitis (UC) is higher than in the general population. However, risk factors of gallstone disease in these patients remain unclear.
Kwangwoo Nam +15 more
doaj +1 more source
A case of chronic recurrent multifocal osteomyelitis associated with Crohn's disease [PDF]
Chronic recurrent multifocal osteomyelitis (CRMO) is an auto-inflammatory bone disease of unknown etiology, most commonly affecting the metaphysis of long bones, especially the tibia, femur and clavicle. The clinical spectrum varies from self-limited uni-
De Baets, Frans +5 more
core

