Results 141 to 150 of about 79,473 (337)

Resolved Hypereosinophilic Syndrome and Immune Thrombocytopenic Purpura in Ulcerative Colitis Patients Post Colectomy: A Case Series and Literature Review

open access: yesJournal of Inflammation Research, 2022
Ahmed Hussein Subki,1 Manal Ismail Bokhary,1 Sultan Abdulrahman Alandijani,1 Mohannad Abdulrahman Aljehani,1 Ahmed Wasel Alharbi,1 May Alzahrani,1 Saud Suliman Almuhammadi,2 Bassim Tahseen Albeirouti,3 Mohamed Abdulmajid Abduljabar,1 Silvio Danese4 ...
Subki AH   +9 more
doaj  

Effectiveness and Safety of a Second JAK Inhibitor in Ulcerative Colitis: The J2J Multicentre Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In total 169 patients already exposed to a JAKi and who received a second JAKi were retrospectively studied across 28 GETAID centres, with 48% reaching steroids‐free clinical remission after induction. Adverse events led to treatment discontinuation in 5% of cases.
Mathilde Osty   +56 more
wiley   +1 more source

Management of an undetectable Diverticular Bleed: A Case Report and Literature review

open access: yesClinical Case Reports
Key Clinical Message Diverticular bleeding is the most common cause of lower gastrointestinal bleeding and accounts for 20.8%–41.6% of cases in the Western world. Management involves initial resuscitation followed by diagnostic assessment. Colonoscopy is
Zubir S. Rentiya   +11 more
doaj   +1 more source

Network Meta‐Analysis: Efficacy of Biological Therapies and Small Molecules as Maintenance Therapy in Ulcerative Colitis

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
This systematic review and network meta‐analysis compares biological therapies and small molecules as maintenance treatments for ulcerative colitis, assessing failure rates across clinical, endoscopic and histological outcomes. Findings reveal differential efficacy in patients naive to or previously exposed to advanced therapies, underscoring the ...
Brigida Barberio   +3 more
wiley   +1 more source

Mutation Analysis of TMB‐High Colorectal Cancer: Insights Into Molecular Pathways and Clinical Implications

open access: yesCancer Science, Volume 116, Issue 4, Page 1082-1093, April 2025.
Colorectal cancer (CRC) tumors with high tumor mutation burden (TMB) often exhibit distinct molecular features, including lower KRAS and higher BRAF mutation frequencies, microsatellite instability (MSI), and a mutational signature linked to the CpG island methylator phenotype (CIMP).
Yuko Chikaishi   +17 more
wiley   +1 more source

BRIP-1 germline mutation and its role in colon cancer: presentation of two case reports and review of literature. [PDF]

open access: yes, 2019
BackgroundHereditary colon cancer is characterized by the inheritance of an abnormal gene mutation which predisposes to malignancy. Recent advances in genomic medicine have identified mutations in "novel" genes as conferring an increased risk of ...
Ali, Mir   +2 more
core  

Patient positioning on the operating table and patient safety: A systematic review and meta‐analysis

open access: yesJournal of Advanced Nursing, EarlyView.
Abstract Aim To identify occurrence of harmful incidents related to patient positioning on operating table. Design Systematic review and meta‐analysis. Data Sources Eight databases including Ovid, Medline, Embase, CINAHL, the Cochrane Library, Epistemonikos, Scopus, Web of Science and Google Scholar were systematically searched from the inception of ...
Signe Berit Bentsen   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy