Results 81 to 90 of about 79,473 (337)

Novel machine‐learning bioinformatics reveal distinct metabolic alterations for enhanced colorectal cancer diagnosis and monitoring

iMetaOmics, EarlyView.
The PANDA pipeline for colorectal cancer (CRC) analysis integrates metabolomic data from LC‐MS with machine learning techniques to classify CRC stages and predict biomarkers. Initially, the raw metabolomic data is processed using partial least squares discriminant analysis (PLS‐DA) to reduce dimensionality and highlight key features.
Rui Xu, Hyein Jung, Fouad Choueiry, Shiqi Zhang, Rachel Pearlman, Heather Hampel, Ning Jin, Jieli Li, Jiangjiang Zhu   +8 more
wiley   +1 more source

Economic evaluation of laparoscopic surgery for colorectal cancer [PDF]

, 2007
Objectives: To assess the cost-effectiveness of laparoscopic surgery compared with open surgery for the treatment of colorectal cancer. Methods: A Markov model was developed to model cost-effectiveness over 25 years.
Aberdeen Health Technology Assessment Group, De Verteuil, Robyn, Hernández, Rodolfo Andrés, Vale, Luke David   +3 more
core   +1 more source

Have we hit the JAK‐pot? Success of selective JAK 1 inhibitor following failure of pan‐JAK inhibitor in refractory pediatric ulcerative colitis

JPGN Reports, EarlyView.
Abstract The treatment options available for pediatric ulcerative colitis (UC) are challenging due to few with Federal Drug Administration approval. Newer medications approved for adults include additional biologics with differing mechanisms of action and small molecule drugs, such as Janus kinase (JAK) inhibitors.
Jessica A. Black, Brad Pasternak
wiley   +1 more source

Comparative study of robotic-assisted vs. laparoscopic surgery for colorectal cancer: a single-center experience

Frontiers in Oncology
BackgroundColorectal cancer (CRC) surgeries are commonly performed using either robotic-assisted colorectal surgery (RACS) or laparoscopic colorectal surgery (LCS).
Wenpeng Wang, Jia Liu, Jiefu Wang, Li Li, Dalu Kong, Junfeng Wang   +5 more
doaj   +1 more source

Accelerated Infliximab Dosing Increases 30-Day Colectomy in Hospitalized Ulcerative Colitis Patients: A Propensity Score Analysis.

Inflammatory Bowel Diseases, 2018
Background Standard outpatient induction dosing of infliximab (IFX) may not be effective in hospitalized ulcerative colitis (UC) patients with higher inflammatory burden and colectomy risk.
Shailja C. Shah, S. Naymagon, H. Panchal, B. Sands, B. Cohen, M. Dubinsky   +5 more
semanticscholar   +1 more source

Upadacitinib for difficult‐to‐treat paediatric Crohn's disease

JPGN Reports, EarlyView.
Abstract Paediatric‐onset inflammatory bowel disease (IBD) has an enormous impact on healthcare systems as it translates to a lifetime of healthcare. Since the approval of anti‐tumour necrosis factor‐alpha agents, it has become evident that in the long journey of paediatric IBD, there is an absolute need for more treatment options.
N. Nedelkopoulou, S. Sharma, M. Khalid, C. Hinchliffe   +3 more
wiley   +1 more source

Effect of prophylactic abdominal drainage on postoperative pain in laparoscopic hemicolectomy for colon cancer: a single-center observational study in Korea

Journal of Minimally Invasive Surgery
Purpose: This study aimed to evaluate the effect of prophylactic abdominal drainage (AD) in laparoscopic hemicolectomy, focusing on assessing postoperative pain outcomes.
Sung Seo Hwang, Heung-Kwon Oh, Hye-Rim Shin, Tae-Gyun Lee, Mi Jeong Choi, Min Hyeong Jo, Hong-min Ahn, Hyeonjeong Park, Hyun Hee Sim, Eunjeong Ji, Anuj Naresh Singhi, Duck-Woo Kim, Sung-Bum Kang   +12 more
doaj   +1 more source

Ileostomy Adenocarcinoma : a case report [PDF]

, 2004
Proctocolectomy is the standard treatment for patients suffering from ulcerative colitis which is long-standing, refractory to pharmacotherapy or otherwise associated with complications.
Abela, Joetienne, LaFerla, Godfrey, Szczepanski, Marcin J.   +2 more
core  

Early Stratification of Patients at Risk for Postoperative Complications after Elective Colectomy [PDF]

arXiv, 2018
Stratifying patients at risk for postoperative complications may facilitate timely and accurate workups and reduce the burden of adverse events on patients and the health system. Currently, a widely-used surgical risk calculator created by the American College of Surgeons, NSQIP, uses 21 preoperative covariates to assess risk of postoperative ...
arxiv  

Role of colectomy in preventing recurrent primary sclerosing cholangitis in liver transplant recipients.

World Journal of Gastroenterology, 2018
AIM To study the published evidence on the impact of colectomy in preventing recurrent primary sclerosing cholangitis (rPSC). METHODS An unrestricted systematic literature search in PubMed, EMBASE, Medline OvidSP, ISI Web of Science, Lista (EBSCO) and ...
B. Buchholz, P. Lykoudis, R. Ravikumar, J. Pollok, G. Fusai   +4 more
semanticscholar   +1 more source