Results 121 to 130 of about 39,764 (292)

Evolution of ideas on microscopic colitis

Терапевтический архив, 2015
The literature review gives the present-day views of the definition, etiology, pathogenesis, diagnosis, and treatment of microscopic colitis (MC). In the present view, MC is an inflammatory bowel disease of unknown etiology, which is characterized by ...
I V Maev, Yu A Kucheryavyi, D N Andreev, S V Cheremushkin   +3 more
doaj  

Immune Checkpoint Inhibitors Induce Intestinal Epithelial Injury and a Senescence‐Like Phenotype

iNew Medicine, EarlyView.
ICI treatment promotes the infiltration of activated immune cells into the intestinal mucosa. This inflammatory microenvironment is associated with significant epithelial injury, characterized by the disruption of the epithelial barrier, the depletion of specialized secretory cell lineages, and the induction of a premature senescence phenotype ...
Juan Wang, Shuang Wu, Shuangbiao Wei, Weizhen Xiang, Jianshang Huang, Lei Xiong, Hua Wang, Li Zuo   +7 more
wiley   +1 more source

Microscopic Colitis: A Key Differential Diagnosis in Chronic Watery Diarrhea

Quality in Sport
INTRODUCTION Microscopic colitis (MC) is an often-overlooked inflammatory disorder of the colon. It presents with persistent, non-bloody, watery diarrhea. The characteristic of the condition is a lack of visible endoscopic abnormalities.
Adrianna Klimczak, Barbara Pietrzak, Mikołaj Patelski, Maciej Czapla, Mateusz Surma, Jakub Molenda, Matylda Kuczma, Wiktoria Kotlarz, Wiktoria Mikusek, Marta Kamińska, Krzysztof Dobrzeniecki   +10 more
doaj   +1 more source

Holistic bone developing microenvironment engineered apoptotic extracellular vesicles recapitulate multidimensional developmental signatures in adult and senile bone repair

Interdisciplinary Medicine, EarlyView.
The developing bone was identified as an M2a‐like macrophage driven immune microenvironment with multidimensional developmental signatures. hME‐ApoEVs were successfully fabricated via stimulating the M2a‐like developing microenvironment in vitro and confirmed its recapitulation of developmental features.
Xiaoran Yu, Jieyun Xu, Yuan Zhao, Xinyu Guo, Hongcheng Chen, Junlong Xue, Yong Ao, Linjun Zhang, Xiaomeng Gao, Xueli Mao, Songtao Shi, Zetao Chen   +11 more
wiley   +1 more source

P69 | Collagenous colitis: an unfamiliar but treatable disease

Italian Journal of Medicine
Introduction: Microscopic colitis is part of the differential diagnosis of chronic watery diarrhea. Colonoscopy is normal, its diagnosis is based on histology and encompasses two entities: collagenous colitis end lymphocytic colitis.
doaj   +1 more source

Tiny carriers, big impact: How Fusobacterium nucleatum extracellular vesicles drive oral diseases and beyond

Interdisciplinary Medicine, EarlyView.
This review explores how Fusobacterium nucleatum extracellular vesicles drive local oral diseases and distal pathologies via sophisticated cross‐compartment cross talk. It highlights the transformative potential of these “tiny carriers” as next‐generation molecular intermediaries for advanced health monitoring and innovative bio‐interventions by ...
Rongyang Ma, Jiahui Huang, Yitong Chen, Haoxuan Wang, Hang Zou, Wanghong Zhao, Zilong Deng   +6 more
wiley   +1 more source

Microscopic Colitis: An In-Depth Pathological Review

SVU - International Journal of Medical Sciences
Microscopic colitis (MC) is a chronic inflammatory disorder of the large bowel that predominantly affects older adults, especially women, and is most often characterized by persistent, watery, non-bloody diarrhea.
Ala M Aljehani*
doaj   +1 more source

Colonic Barrier Dysfunction and Inflammation Induced by Nano‐/Micro‐Plastics Fibers in Mice via the FAK/NF‐κB/iNOS and TLR4/NF‐κB/iNOS Pathways

Journal of Applied Toxicology, EarlyView.
ABSTRACT As emerging environmental contaminants, nano‐ and micro‐plastics (NMPs) have drawn increasing research attention due to potential hazards to organisms. Particle shape is a key factor influencing the toxic effects of NMPs, and NMPs of different shapes cause varying degrees of tissue damage. We investigated the specific mechanisms of polystyrene
Yuting Li, Shibo Bao, Puyang Huang, Jiahui Wang, Hongfeng Li, Yahong Liu, Kai Wang, Jianjun Du, Lingjun Yan, Guowei Pan, Wei Sun   +10 more
wiley   +1 more source

Chronic Diarrhea Owing to Microscopic Colitis: A Cohort Study with Insights into Diagnostic Challenges and Size of the Problem

Diagnostics
Background: Microscopic colitis (MC) is a recognized cause of chronic diarrhea and is often underestimated when a colonoscopy appears normal. This study aims to accurately diagnose chronic diarrhea through histopathological examination of colonoscopic ...
Ahmed Ibrahim Gad, Sara Mohamed Salem, Hanaa A. Nofal, Hayam Rashed, Hossam Tharwat Ali, Noura Almadani, Rasha Mahfouz, Nevin F. Ibrahim, Ayman M. E. M. Sadek   +8 more
doaj   +1 more source

Protective Role of Polydatin Against Vancomycin‐Induced Lung Toxicity via Oxidative Stress, Inflammation, Endoplasmic Reticulum Stress, Apoptosis, and Ferroptosis Pathways

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study aimed to evaluate whether polydatin (Poly) could eliminate the harmful effects of vancomycin (VCM) on the lungs of rats. Rats were administered VCM (200 mg/kg) and Poly (50 mg/kg), both separately and in combination, for a duration of 7 days.
Serpil Aygörmez, Sefa Küçükler, Selim Çomaklı, Hasan Şimşek, Özge Kandemir, Fatih Mehmet Kandemir, Şaban Maraşlı   +6 more
wiley   +1 more source