Results 1 to 10 of about 26,503 (228)

Acetylcysteine and budesonide for the treatment of refractory Mycoplasma pneumoniae pneumonia in children: a clinical observation

Italian Journal of Pediatrics, 2023
Background To examine the clinical impact of bronchoscope alveolar lavage (BAL) combination with budesonide, ambroxol + budesonide, or acetylcysteine + budesonide in the treatment of refractory Mycoplasma pneumoniae pneumonia (RMPP).
Yanli Wang, Kai Liu, Chuangui Chen, Chengyun Zhang   +3 more
doaj   +1 more source

Budesonide Analogues Preserve Stem Cell Pluripotency and Delay 3D Gastruloid Development

Pharmaceutics, 2023
Small molecules that can modulate or stabilize cell–cell interactions are valuable tools for investigating the impact of collective cell behavior on various biological processes such as development/morphogenesis, tissue regeneration and cancer ...
Filomena Amoroso, Eduardo Ibello, Federica Saracino, Federica Cermola, Giovanna Ponticelli, Enrica Scalera, Francesca Ricci, Gino Villetti, Gilda Cobellis, Gabriella Minchiotti, Eduardo Jorge Patriarca, Dario De Cesare, Cristina D’Aniello   +12 more
doaj   +1 more source

Biophysical and chemical stability of surfactant/budesonide and the pulmonary distribution following intra-tracheal administration

Drug Delivery, 2019
Intra-tracheal instillation of budesonide using surfactant as a vehicle significantly decreased the incidence of bronchopulmonary dysplasia or death in preterm infants.
Chung-Ming Chen, Chien-Hsiang Chang, Chih-Hua Chao, Mei-Hui Wang, Tsu-Fu Yeh   +4 more
doaj   +1 more source

Intranasal Application of Budesonide Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Suppressing Nucleotide-Binding Oligomerization Domain-Like Receptor Family, Pyrin Domain-Containing 3 Inflammasome Activation in Mice

Journal of Immunology Research, 2019
Aim. To investigate the protective effects of budesonide against lipopolysaccharide- (LPS-) induced acute lung injury (ALI) in a murine model and its underlying mechanism. Methods. Adult male C57BL/6 mice were divided into three groups: control, ALI, and
Liang Dong, Yu-Hang Zhu, De-Xing Liu, Juan Li, Peng-Cheng Zhao, Yuan-Ping Zhong, Yong-Qin Chen, Wei Xu, Zhao-Qiong Zhu   +8 more
doaj   +1 more source

Altered Frequency of NK Cells and Treg Cells by Astragalus Polysaccharide Combined with Budesonide in Asthma Model Mice

Advances in Polymer Technology, 2020
Objective. We investigated the efficacy of astragalus polysaccharide (APS) combined with budesonide and the effect on expressions of peripheral NK cells and Treg cells and the molecular mechanism in mice with bronchial asthma. Methods.
Wei Zhang, Kuifen Ma
doaj   +1 more source

Dose-response relationship of ICS/fast-onset LABA as reliever therapy in asthma

BMC Pulmonary Medicine, 2019
Background and objective The dose-response relationship of inhaled corticosteroid (ICS)/fast-onset long acting beta agonist (LABA) reliever therapy has not been formally addressed.
Richard Beasley, James Harper, Grace Bird, Harriette Dunphy, Alex Semprini, Ian D. Pavord, Alberto Papi, Mark Weatherall   +7 more
doaj   +1 more source

Effect of Surfactant and Budesonide on the Pulmonary Distribution of Fluorescent Dye in Mice

Pediatrics and Neonatology, 2015
Surfactant is a useful vehicle for the intratracheal delivery of medicine to the distal lung. The aim of this study was to analyze the effect of intratracheal surfactant and budesonide instillation on the pulmonary distribution of fluorescent dye in mice.
Liang-Ti Huang, Tsu-Fu Yeh, Yu-Lin Kuo, Pin-Chuan Chen, Chung-Ming Chen   +4 more
doaj   +1 more source

Efficacy of budesonide/formoterol maintenance and reliever therapy compared with higher-dose budesonide as step-up from low-dose inhaled corticosteroid treatment

BMC Pulmonary Medicine, 2017
Background Asthma management may involve a step up in treatment when symptoms are not well controlled. We examined whether budesonide/formoterol maintenance and reliever therapy (MRT) is as effective as higher, fixed-dose budesonide plus as-needed ...
Christine R. Jenkins, Göran Eriksson, Eric D. Bateman, Helen K. Reddel, Malcolm R. Sears, Magnus Lindberg, Paul M. O’Byrne   +6 more
doaj   +1 more source

Risk of active tuberculosis among COPD patients treated with fixed combinations of long-acting beta2 agonists and inhaled corticosteroids

BMC Infectious Diseases, 2020
Objectives To investigate the incidence of active tuberculosis (TB) among COPD patients using fluticasone/salmeterol or budesonide/formoterol, and to identify any differences between these two groups of patients.
Tsan-Ming Huang, Kuan-Chih Kuo, Ya-Hui Wang, Cheng-Yi Wang, Chih-Cheng Lai, Hao-Chien Wang, Likwang Chen, Chong-Jen Yu, On the behalf of Taiwan Clinical Trial Consortium for Respiratory Diseases (TCORE)   +8 more
doaj   +1 more source

The Effect of Three Forms of Local Corticosteroids on Sinonasal Polyposis [PDF]

Iranian Journal of Otorhinolaryngology
Introduction: Since sinonasal polyposis (SNP) has a high recurrence rate after surgery, various studies have investigated the effect of corticosteroid medications to prevent disease recurrence.
Matin Ghazizadeh, Ali Goljanian Tabrizi, Najmeh Rajabi   +2 more
doaj   +1 more source