New Strategies for Improving Budesonide Skin Retention [PDF]
The aim of this work was to evaluate the ex vivo effect of the combination of two strategies, complexation with cyclodextrin, and poloxamer hydrogels, for improving water solubility in the dermal absorption of budesonide.
Cristina Padula +3 more
doaj +3 more sources
Sally Hollis,1 Carin Jorup,2 Dan Lythgoe,3 Gunnar Martensson,2 Pontus Regnell,2 Göran Eckerwall2 1AstraZeneca R&D, Alderley Park, Macclesfield, UK; 2AstraZeneca R&D, Gothenburg, Sweden; 3Phastar, Chiswick, London, UK Background: Concerns ...
Hollis S +5 more
doaj +1 more source
Effects of Budesonide on Coronavirus-Associated Receptor and Immune-Mediator Expression in Human Lung Microvascular Endothelial Cells [PDF]
Background and Objectives: Inhaled corticosteroids exert broad immunomodulatory effects in patients with chronic airway diseases. However, their direct impact on pulmonary endothelial immune responses and coronavirus-associated receptor expression ...
Izabela Ławska +3 more
doaj +2 more sources
Decreased frequency of adenoidectomy by a 12-week nasal budesonide treatment
Haiyu Hong,1,* Fenghong Chen,2,* Xiaobin Zheng,3 Wei Liao,1 Zhenpeng Liao,1 Yujie Cao,2 Haixin He,1 Zhe Zhu,4,5 Yunping Fan1 1Department of Otolaryngology and Head Neck Surgery of 5th Hospital, Affiliated with Sun Yat-sen University, Zhuhai, 2Department
Hong H +8 more
doaj +1 more source
Increased failure of budesonide MMX for ulcerative colitis during the COVID-19 pandemic: a population-based study [PDF]
Background: Corticosteroids induce remission in ulcerative colitis (UC) but are associated with adverse effects, including prednisone ⩾20 mg/day associated with serious COVID-19 outcomes.
Stephanie Coward +10 more
doaj +2 more sources
Long-term safety and efficacy of budesonide in the treatment of ulcerative colitis
Marisa Iborra,1 Diego Álvarez-Sotomayor,2 Pilar Nos1 1Gastroenterology Unit, Department of Digestive Disease, Centro de investigación biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), La Fe University and ...
Iborra M +2 more
doaj +1 more source
Cost-effectiveness of as-needed budesonide-formoterol in adults with mild asthma: the Novel START trial [PDF]
Background The Global Initiative for Asthma recommends as-needed combination inhaled corticosteroid-formoterol reliever for mild asthma. Its cost-effectiveness is uncertain outside double-blind regulatory trials.
William Leung +13 more
doaj +2 more sources
Background: Previous studies suggest that inhaled budesonide-formoterol used as needed could effectively reduce the severe exacerbation of mild persistent asthma.
Xiang Tong +4 more
doaj +1 more source
Direct lung administration of budesonide in combination with surfactant reduces the incidence of bronchopulmonary dysplasia. Although the therapy is currently undergoing clinical development, the lung distribution of budesonide throughout the premature ...
Riccardo Zecchi +12 more
doaj +1 more source
Simultaneous intratracheal administration of surfactant and budesonide in the prevention of bronchopulmonary dysplasia in the treatment of respiratory distress syndrome in premature infants [PDF]
Background: Premature birth is an important issue in developing and developed countries. The purpose of this study is to investigate the effect of budesonide and surfactant in the treatment of respiratory distress syndrome and the prevention of ...
Norouzi, Elahe +4 more
core +1 more source

