Results 11 to 20 of about 24,788 (241)

Risk of pneumonia with budesonide-containing treatments in COPD: an individual patient-level pooled analysis of interventional studies

International Journal of COPD, 2017
Sally Hollis,1 Carin Jorup,2 Dan Lythgoe,3 Gunnar Martensson,2 Pontus Regnell,2 Göran Eckerwall2 1AstraZeneca R&D, Alderley Park, Macclesfield, UK; 2AstraZeneca R&D, Gothenburg, Sweden; 3Phastar, Chiswick, London, UK Background: Concerns ...
Hollis S, Jorup C, Lythgoe D, Martensson G, Regnell P, Eckerwall G   +5 more
doaj   +1 more source

Decreased frequency of adenoidectomy by a 12-week nasal budesonide treatment

Therapeutics and Clinical Risk Management, 2017
Haiyu Hong,1,* Fenghong Chen,2,* Xiaobin Zheng,3 Wei Liao,1 Zhenpeng Liao,1 Yujie Cao,2 Haixin He,1 Zhe Zhu,4,5 Yunping Fan1 1Department of Otolaryngology and Head Neck Surgery of 5th Hospital, Affiliated with Sun Yat-sen University, Zhuhai, 2Department
Hong H, Chen F, Zheng X, Liao W, Liao Z, Cao Y, He H, Zhu Z, Fan Y   +8 more
doaj   +1 more source

Three-dimensional environment sensitizes pancreatic cancer cells to the anti-proliferative effect of budesonide by reprogramming energy metabolism [PDF]

Journal of Experimental & Clinical Cancer Research
Background Pancreatic ductal adenocarcinoma (PDAC) is the most lethal cancer with an aggressive metastatic phenotype and very poor clinical prognosis.
Eduardo Ibello, Federica Saracino, Donatella Delle Cave, Silvia Buonaiuto, Filomena Amoroso, Gennaro Andolfi, Marco Corona, Ombretta Guardiola, Vincenza Colonna, Bruno Sainz Jr, Lucia Altucci, Dario De Cesare, Gilda Cobellis, Enza Lonardo, Eduardo Jorge Patriarca, Cristina D’Aniello, Gabriella Minchiotti   +16 more
doaj   +2 more sources

Long-term safety and efficacy of budesonide in the treatment of ulcerative colitis

Clinical and Experimental Gastroenterology, 2014
Marisa Iborra,1 Diego Álvarez-Sotomayor,2 Pilar Nos1 1Gastroenterology Unit, Department of Digestive Disease, Centro de investigación biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), La Fe University and ...
Iborra M, Álvarez-Sotomayor D, Nos P   +2 more
doaj   +1 more source

A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation

Hepatology, EarlyView., 2022
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole, Kristin Kaasen Jørgensen, Kristian Holm, Peder R. Braadland, Malin Holm Meyer‐Myklestad, Asle Wilhelm Medhus, Dag Henrik Reikvam, Alexandra Götz, Krzysztof Grzyb, Kirsten Muri Boberg, Tom Hemming Karlsen, Martin Kummen, Johannes R. Hov   +12 more
wiley   +1 more source

Simultaneous intratracheal administration of surfactant and budesonide in the prevention of bronchopulmonary dysplasia in the treatment of respiratory distress syndrome in premature infants

, 2023
Background: Premature birth is an important issue in developing and developed countries. The purpose of this study is to investigate the effect of budesonide and surfactant in the treatment of respiratory distress syndrome and the prevention of ...
Norouzi, Elahe, Aminyan Daryasari, Arezoo, Maleki, Mahsa, Farhanian, Fahimeh, Kashaki, Mandana   +4 more
core   +1 more source

Self-Immolative Carbamate Linkers for CD19-Budesonide Antibody-Drug Conjugates

, 2023
Antibody-drug conjugates consist of potent small molecule payloads linked to a targeting antibody. Payloads must possess a viable functional group by which a linker for conjugation can be attached.
Axel, Hernandez, Jr., Martin, Hayes, Michael, McPherson, Agnieszka, Bischoff, Thomas, Vargo, Margaret, Fettis, Lu, Wang, Yu, Tian, Adrian, Hobson, Ying, Jia, Jason, Oh, Christopher, Marvin, Theresa, Dunstan   +12 more
core   +1 more source

Biophysical and chemical stability of surfactant/budesonide and the pulmonary distribution following intra-tracheal administration

Drug Delivery, 2019
Intra-tracheal instillation of budesonide using surfactant as a vehicle significantly decreased the incidence of bronchopulmonary dysplasia or death in preterm infants.
Chung-Ming Chen, Chien-Hsiang Chang, Chih-Hua Chao, Mei-Hui Wang, Tsu-Fu Yeh   +4 more
doaj   +1 more source

Intranasal Application of Budesonide Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Suppressing Nucleotide-Binding Oligomerization Domain-Like Receptor Family, Pyrin Domain-Containing 3 Inflammasome Activation in Mice

Journal of Immunology Research, 2019
Aim. To investigate the protective effects of budesonide against lipopolysaccharide- (LPS-) induced acute lung injury (ALI) in a murine model and its underlying mechanism. Methods. Adult male C57BL/6 mice were divided into three groups: control, ALI, and
Liang Dong, Yu-Hang Zhu, De-Xing Liu, Juan Li, Peng-Cheng Zhao, Yuan-Ping Zhong, Yong-Qin Chen, Wei Xu, Zhao-Qiong Zhu   +8 more
doaj   +1 more source

Altered Frequency of NK Cells and Treg Cells by Astragalus Polysaccharide Combined with Budesonide in Asthma Model Mice

Advances in Polymer Technology, 2020
Objective. We investigated the efficacy of astragalus polysaccharide (APS) combined with budesonide and the effect on expressions of peripheral NK cells and Treg cells and the molecular mechanism in mice with bronchial asthma. Methods.
Wei Zhang, Kuifen Ma
doaj   +1 more source