Results 21 to 30 of about 26,503 (228)

Asthma control with ICS-formoterol reliever versus maintenance ICS and SABA reliever therapy: a post hoc analysis of two randomised controlled trials

BMJ Open Respiratory Research, 2022
Background In randomised controlled trials, as-needed inhaled corticosteroid (ICS)-formoterol reliever therapy reduces severe exacerbation risk compared with maintenance ICS plus short-acting beta2-agonist (SABA) reliever in adolescent and adult asthma ...
, James Fingleton, Mark Weatherall, Richard Beasley, Irene Braithwaite, Ian Pavord, Jenny Sparks, Lee Hatter, Helen K Reddel, Robert J Hancox, Mark Holliday, Andrew Corin, Daniela Hall, Claire Houghton, Saras Mane, John Martindale, Karen Oldfield, Donah Sabbagh, Alexandra Vohlidkova, Alberto Papi, Allie Eathorne, Pepa Bruce   +21 more
doaj   +1 more source

A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation

Hepatology, EarlyView., 2022
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole, Kristin Kaasen Jørgensen, Kristian Holm, Peder R. Braadland, Malin Holm Meyer‐Myklestad, Asle Wilhelm Medhus, Dag Henrik Reikvam, Alexandra Götz, Krzysztof Grzyb, Kirsten Muri Boberg, Tom Hemming Karlsen, Martin Kummen, Johannes R. Hov   +12 more
wiley   +1 more source

Self-Immolative Carbamate Linkers for CD19-Budesonide Antibody-Drug Conjugates [PDF]

, 2023
Antibody-drug conjugates consist of potent small molecule payloads linked to a targeting antibody. Payloads must possess a viable functional group by which a linker for conjugation can be attached.
Axel, Hernandez, Jr., Martin, Hayes, Michael, McPherson, Agnieszka, Bischoff, Thomas, Vargo, Margaret, Fettis, Lu, Wang, Yu, Tian, Adrian, Hobson, Ying, Jia, Jason, Oh, Christopher, Marvin, Theresa, Dunstan   +12 more
core   +2 more sources

Impact of Regional Hepatic Immunosuppression With Budesonide on Bacterial Elimination in Porcine Abdominal Sepsis. [PDF]

Acta Anaesthesiol Scand
ABSTRACT Introduction The liver is essential for bacterial elimination, preventing intestinal bacteria from entering the systemic circulation, and for producing inflammatory cytokines. Glucocorticoids have been reported to exert heterogeneous effects on bacterial clearance in sepsis.
Hanslin K, Skorup P, Wilske F, Larsson A, Tano E, Sjölin J, Lipcsey M.   +6 more
europepmc   +2 more sources

Efficacy and safety of oral beclomethasone dipropionate and budesonide MMX 5-aminosalicylates or placebo in ulcerative colitis: a systematic review and meta-analysis

Therapeutic Advances in Gastroenterology, 2023
Background: Low bioavailability steroids, including beclomethasone dipropionate (BDP) and budesonide MMX, have been developed to ensure colonic targeting and low systemic activity than systematic corticosteroids in treating patients with ulcerative ...
Brigida Barberio, Ilaria Marsilio, Andrea Buda, Luisa Bertin, Gianluca Semprucci, Annalisa Zanini, Martina Crepaldi, Fabiana Zingone, Edoardo Savarino   +8 more
doaj   +1 more source

Combination formoterol and budesonide as maintenance and reliever therapy versus combination inhaler maintenance for chronic asthma in adults and children. [PDF]

, 2013
BACKGROUND: Asthma is characterised by chronic inflammation of the airways and recurrent exacerbations with wheezing, chest tightness and cough. Treatment with inhaled steroids and bronchodilators often results in good control of symptoms, prevention of ...
Mindus, SM, Ferrara, G, Ferrara, G,, Kew, KM, Karner, C   +4 more
core   +1 more source

Bowel frequency (night) and urgent defecation are improved by budesonide foam in patients with ulcerative colitis: a retrospective observational study

BMC Gastroenterology, 2022
Introduction Patients with ulcerative colitis (UC) are known to have a significantly poor quality of life due to bowel frequency (night) and urgent defecation.
Ryosuke Miyazaki, Toshiyuki Sakurai, Mariko Shimada, Yuko Iwashita, Naoki Shibuya, Yoshihiro Akita, Haruna Miyashita, Yuki Maruyama, Masayuki Saruta   +8 more
doaj   +1 more source

Combination fluticasone and salmeterol versus fixed dose combination budesonide and formoterol for chronic asthma in adults and children [PDF]

, 2008
BackgroundCombination therapies are frequently recommended as maintenance therapy for people with asthma, whose disease is not adequately controlled with inhaled steroids.
Christopher J Cates, Lasserson, TJ, Giovanni Ferrara, Ferrara, G, Toby J Lasserson, Cates, CJ, Casali, L, Lucio Casali   +7 more
core   +1 more source

Development and validation of analytical methods for selective determination of albuterol and budesonide in Airsupra inhalation aerosol using spectrophotometry

Scientific Reports, 2023
Airsupra inhalation aerosol is a recently approved FDA medication that combines albuterol and budesonide for treating or preventing bronchoconstriction and lowering the risk of relapses in asthma patients who are 18 years of age and older. To selectively
Atiah H. Almalki, Sherif Ramzy, Ahmed A. Almrasy   +2 more
doaj   +1 more source

Inhaled steroids and risk of pneumonia for chronic obstructive pulmonary disease. [PDF]

, 2014
BACKGROUND: Inhaled corticosteroids (ICS) are anti-inflammatory drugs that have proven benefits for people with worsening symptoms of chronic obstructive pulmonary disease (COPD) and repeated exacerbations.
Seniukovich, A, Alieksei Seniukovich, Kew, KM, Kayleigh M Kew   +3 more
core   +1 more source