Results 31 to 40 of about 20,955 (176)

Risk of active tuberculosis among COPD patients treated with fixed combinations of long-acting beta2 agonists and inhaled corticosteroids

BMC Infectious Diseases, 2020
Objectives To investigate the incidence of active tuberculosis (TB) among COPD patients using fluticasone/salmeterol or budesonide/formoterol, and to identify any differences between these two groups of patients.
Tsan-Ming Huang, Kuan-Chih Kuo, Ya-Hui Wang, Cheng-Yi Wang, Chih-Cheng Lai, Hao-Chien Wang, Likwang Chen, Chong-Jen Yu, On the behalf of Taiwan Clinical Trial Consortium for Respiratory Diseases (TCORE)   +8 more
doaj   +1 more source

Achieving clinical and histologic remission with tezepelumab in an adolescent with refractory eosinophilic gastrointestinal disease: A case report [PDF]

JPGN Rep
Abstract Tezepelumab is a human monoclonal antibody that binds to human thymic stromal lymphopoietin (TSLP), an epithelial cytokine that plays a role in Type 2 signaling. We describe a 17‐year‐old with a history of eosinophilic esophagitis (EoE) and eosinophilic gastroenteritis who demonstrated response to tezepelumab with both clinical and histologic ...
Newsome D, Sharlin C, Bauer C, Schroeder S.   +3 more
europepmc   +2 more sources

Increased FKBP51 in induced sputum cells of chronic obstructive pulmonary disease patients after therapy

European Journal of Medical Research, 2009
Objective Immunophilin FKBP51 assists polypeptide folding, participates in glucocorticoid actions and may play a role in glucocorticoid resistance. FKBP51 is altered in patients with asthma, but its role in chronic obstructive pulmonary disease (COPD ...
Holownia A, Mroz R M, Kolodziejczyk A, Chyczewska E, Braszko J J   +4 more
doaj   +1 more source

A real-world cost-effectiveness analysis of nebulized budesonide and intravenous methylprednisolone in acute exacerbation of chronic obstructive pulmonary disease

Frontiers in Pharmacology, 2022
Objective: To assess the cost-effectiveness of nebulized budesonide and intravenous methylprednisolone in the treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) in a real-world setting.Materials and methods: Data from 291 ...
Yong-Li Gu, Zeng-Xian Sun, Ying Sun, Yan Wen, Xin Guan, Dao-Li Jiang, Cong Cheng, Huan Gu   +7 more
doaj   +1 more source

Long-Term Oral Budesonide Use in Inflammatory Bowel Disease: Effects on Bone Mineral Density and Late-Onset Adverse Events

Diagnostics
Background/Objectives: Budesonide is a corticosteroid with low systemic bioavailability, commonly used for localized treatment in inflammatory bowel disease (IBD).
Tugce Eskazan, Oguz Kagan Bakkaloglu, Emre Durcan, Atilla Akpinar, Enes Ali Kurt, Ugur Onal, Yusuf Ziya Erzin, Ali Ibrahim Hatemi, Aykut Ferhat Celik   +8 more
doaj   +1 more source

Old disease, new twist

Journal of Hospital Medicine, EarlyView.
Abstract An 81‐year‐old man with a history of high‐grade urothelial carcinoma of the bladder and ureter on treatment with atezolizumab and tiragolumab presented to the emergency department with 5 months of malaise, generalized weakness, and fatigue and 2 weeks of subjective fevers. One month prior to presentation, he received an empiric 9‐day course of
Hadi Roudsari, Gurpreet Dhaliwal, Anand D. Jagannath, Alan H. Baik, Sam Brondfield   +4 more
wiley   +1 more source

Role of Erythromycin-Regulated Histone Deacetylase-2 in Benign Tracheal Stenosis

Canadian Respiratory Journal, 2020
Objective. This study aims to explore the role of erythromycin-regulated histone deacetylase-2 in benign tracheal stenosis. Methods. The rabbit model of tracheal stenosis was established. The rabbits were randomly divided into 8 groups.
Zhenjie Huang, Peng Wei, Luoman Gan, Tonghua Zeng, Caicheng Qin, Guangnan Liu   +5 more
doaj   +1 more source

Growth and development in paediatric onset inflammatory bowel disease: Data analysis from the CEDATA registry

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objective Different therapies may affect the growth and development of children and adolescents with inflammatory bowel disease (IBD) supporting specific therapy algorithms for paediatric Crohn's disease (CD) and ulcerative colitis (UC). Methods Growth and development data from the German–Austrian CEDATA‐GPGE registry entered between 2004 and ...
Anna Schmidt, Ilse Broekaert, Christoph Hünseler, Jan de Laffolie, CEDATA Study Group   +4 more
wiley   +1 more source

Association of attention‐deficit/hyperactivity disorder and autism with inflammatory bowel disease activity

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives To estimate the effect of attention deficit hyperactivity disorder (ADHD) and autism on the disease activity of inflammatory bowel disease (IBD) in pediatric and young patients. Methods Patients diagnosed with IBD between the ages of 6 and 24 years were identified in Danish nationwide registries 1996–2022.
Sabine Jansson, Mads Damsgaard Wewer, Johan Burisch, Matthew P. Fox, Michael E. Benros, Charlotte Ulrikka Rask, Vibeke Wewer, Mikkel Malham   +7 more
wiley   +1 more source

Risk of pneumonia with budesonide-containing treatments in COPD: an individual patient-level pooled analysis of interventional studies

International Journal of COPD, 2017
Sally Hollis,1 Carin Jorup,2 Dan Lythgoe,3 Gunnar Martensson,2 Pontus Regnell,2 Göran Eckerwall2 1AstraZeneca R&D, Alderley Park, Macclesfield, UK; 2AstraZeneca R&D, Gothenburg, Sweden; 3Phastar, Chiswick, London, UK Background: Concerns ...
Hollis S, Jorup C, Lythgoe D, Martensson G, Regnell P, Eckerwall G   +5 more
doaj